Yonghoon Kwon
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Explore the profile of Yonghoon Kwon including associated specialties, affiliations and a list of published articles.
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33
Citations
779
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Recent Articles
11.
Tenner B, Zhang J, Kwon Y, Pessino V, Feng S, Huang B, et al.
Sci Adv
. 2021 May;
7(21).
PMID: 34020947
Growing evidence suggests that many essential intracellular signaling events are compartmentalized within kinetically distinct microdomains in cells. Genetically encoded fluorescent biosensors are powerful tools to dissect compartmentalized signaling, but current...
12.
Hong S, Seo S, Woo S, Kwon Y, Song M, Ha N
J Agric Food Chem
. 2021 May;
69(21):5948-5954.
PMID: 34015930
SARS-CoV-2, the coronavirus strain that initiated the COVID-19 pandemic, and its subsequent variants present challenges to vaccine development and treatment. As the coronavirus evades the host innate immune response at...
13.
Song P, Jo H, Shim W, Kwon Y, Bae S, Kwon Y, et al.
Exp Ther Med
. 2021 Mar;
21(5):420.
PMID: 33747160
Fibrillar collagen and elastic fibers are the main components of the dermal extracellular matrix (ECM), which confers mechanical strength and resilience to the skin. In particular, type I collagen produced...
14.
Chang Y, Kim D, Zhou K, Jeong M, Park S, Kwon Y, et al.
Exp Mol Med
. 2021 Mar;
53(3):384-392.
PMID: 33654221
Single-molecule localization microscopy (SMLM) has allowed the observation of various molecular structures in cells beyond the diffraction limit using organic dyes. In principle, the SMLM resolution depends on the precision...
15.
Jeong M, Zhou K, Park S, An H, Kwon Y, Chang Y, et al.
Exp Mol Med
. 2021 Feb;
53(2):291-299.
PMID: 33603128
Various repertoires of membrane protein interactions determine cellular responses to diverse environments around cells dynamically in space and time. Current assays, however, have limitations in unraveling these interactions in the...
16.
Schulthoff S, Hamilton J, Heinrich M, Kwon Y, Wirtz C, Furstner A
Angew Chem Int Ed Engl
. 2020 Sep;
60(1):446-454.
PMID: 32946141
Total synthesis allowed the constitution of the cytotoxic marine macrolides of the formosalide family to be confirmed and their previously unknown stereostructure to be assigned with confidence. The underlying blueprint...
17.
Song P, Kwon Y, Joo J, Kim D, Yoon J
Int J Mol Sci
. 2019 Aug;
20(16).
PMID: 31405033
Secretory proteins play important roles in the cross-talk of individual functional units, including cells. Since secretory proteins are essential for signal transduction, they are closely related with disease development, including...
18.
Kim D, Park S, Kim D, Jeong M, Noh J, Kwon Y, et al.
PLoS Biol
. 2018 Dec;
16(12):e2006660.
PMID: 30543635
Interactions between membrane proteins are poorly understood despite their importance in cell signaling and drug development. Here, we present a co-immunoimmobilization assay (Co-II) enabling the direct observation of membrane protein...
19.
Chelakkot C, Choi Y, Kim D, Park H, Ghim J, Kwon Y, et al.
Exp Mol Med
. 2018 Feb;
50(2):e450.
PMID: 29472701
The gut microbiota has an important role in the gut barrier, inflammation and metabolic functions. Studies have identified a close association between the intestinal barrier and metabolic diseases, including obesity...
20.
Gelozia S, Kwon Y, McDonald R, West F
Chemistry
. 2018 Feb;
24(23):6052-6056.
PMID: 29444379
Organoaluminum-mediated double interrupted Nazarov cyclization to access bicyclo[3.1.0]hexanols via nucleophilic methyl attack followed by Simmons-Smith-type electrophilic cyclopropanation is reported. These alcohols can undergo ring opening to afford cyclohexanones or cyclohexenones,...