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Yonca B Karadeniz

Explore the profile of Yonca B Karadeniz including associated specialties, affiliations and a list of published articles. Areas
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Citations 159
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Recent Articles
1.
Burrus C, McKinstry S, Kim N, Ozlu M, Santoki A, Fang F, et al.
Cell Rep . 2020 Jan; 30(3):642-657.e6. PMID: 31968243
Huntington's disease (HD) is caused by an autosomal dominant polyglutamine expansion mutation of Huntingtin (HTT). HD patients suffer from progressive motor, cognitive, and psychiatric impairments, along with significant degeneration of...
2.
Neukomm L, Burdett T, Seeds A, Hampel S, Coutinho-Budd J, Farley J, et al.
Neuron . 2017 Jul; 95(1):78-91.e5. PMID: 28683272
Axon degeneration is a hallmark of neurodegenerative disease and neural injury. Axotomy activates an intrinsic pro-degenerative axon death signaling cascade involving loss of the NAD biosynthetic enzyme Nmnat/Nmnat2 in axons,...
3.
McKinstry S, Karadeniz Y, Worthington A, Hayrapetyan V, Ozlu M, Serafin-Molina K, et al.
J Neurosci . 2014 Jul; 34(28):9455-72. PMID: 25009276
Huntington's disease (HD) is a neurodegenerative disease caused by the expansion of a poly-glutamine (poly-Q) stretch in the huntingtin (Htt) protein. Gain-of-function effects of mutant Htt have been extensively investigated...