Cagla Eroglu
Overview
Explore the profile of Cagla Eroglu including associated specialties, affiliations and a list of published articles.
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66
Citations
4729
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Recent Articles
1.
Salazar M, Kolanukuduru S, Ramirez V, Lyu B, Sejourne G, Sesaki H, et al.
bioRxiv
. 2024 Nov;
PMID: 39484572
Dysfunctional mitochondrial dynamics are a hallmark of devastating neurodevelopmental disorders such as childhood refractory epilepsy. However, the role of glial mitochondria in proper brain development is not well understood. We...
2.
Sejourne G, Eroglu C
Curr Opin Neurobiol
. 2024 Oct;
89:102925.
PMID: 39357429
A fundamental feature shared across neurodevelopmental disorders (NDDs) is the disruption of synaptic circuit formation and homeostasis. During early life, non-neuronal cells called astrocytes tightly regulate the establishment of circuits...
3.
Savage J, Ramirez J, Risher W, Wang Y, Irala D, Eroglu C
Cell Rep Methods
. 2024 Sep;
4(9):100861.
PMID: 39255792
The formation of precise numbers of neuronal connections, known as synapses, is crucial for brain function. Therefore, synaptogenesis mechanisms have been one of the main focuses of neuroscience. Immunohistochemistry is...
4.
Wang S, Baumert R, Sejourne G, Bindu D, Dimond K, Sakers K, et al.
bioRxiv
. 2024 Sep;
PMID: 39253496
Astrocytes, a major glial cell type of the brain, regulate synapse numbers and function. However, whether astrocyte dysfunction can cause synaptic pathologies in neurological disorders such as Parkinson's Disease (PD)...
5.
Irala D, Wang S, Sakers K, Nagendren L, Ulloa Severino F, Bindu D, et al.
Neuron
. 2024 Apr;
112(10):1657-1675.e10.
PMID: 38574730
Astrocytes strongly promote the formation and maturation of synapses by secreted proteins. Several astrocyte-secreted synaptogenic proteins controlling excitatory synapse development were identified; however, those that induce inhibitory synaptogenesis remain elusive....
6.
Colon Ortiz C, Eroglu C
Curr Opin Cell Biol
. 2023 Dec;
86:102307.
PMID: 38145604
Multiple Sclerosis (MS) is a common cause of impairment in working-aged adults. MS is characterized by neuroinflammation and infiltration of peripheral immune cells to the brain, which cause myelin loss...
7.
δ-Catenin controls astrocyte morphogenesis via layer-specific astrocyte-neuron cadherin interactions
Tan C, Bindu D, Hardin E, Sakers K, Baumert R, Ramirez J, et al.
J Cell Biol
. 2023 Sep;
222(11).
PMID: 37707499
Astrocytes control the formation of specific synaptic circuits via cell adhesion and secreted molecules. Astrocyte synaptogenic functions are dependent on the establishment of their complex morphology. However, it is unknown...
8.
Ulloa Severino F, Lawal O, Sakers K, Wang S, Kim N, Friedman A, et al.
Nat Commun
. 2023 Sep;
14(1):5522.
PMID: 37684234
Synaptogenesis is essential for circuit development; however, it is unknown whether it is critical for the establishment and performance of goal-directed voluntary behaviors. Here, we show that operant conditioning via...
9.
Savage J, Ramirez J, Risher W, Wang Y, Irala D, Eroglu C
bioRxiv
. 2023 Jul;
PMID: 37425715
The formation of precise numbers of neuronal connections, known as synapses, is crucial for brain function. Therefore, synaptogenesis mechanisms have been one of the main focuses of neuroscience. Immunohistochemistry is...
10.
Chen X, Wolfe D, Bindu D, Zhang M, Taskin N, Goertsen D, et al.
Nat Commun
. 2023 Jun;
14(1):3345.
PMID: 37291094
Delivering genes to and across the brain vasculature efficiently and specifically across species remains a critical challenge for addressing neurological diseases. We have evolved adeno-associated virus (AAV9) capsids into vectors...