M Ilcim Ozlu
Overview
Explore the profile of M Ilcim Ozlu including associated specialties, affiliations and a list of published articles.
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4
Citations
502
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Recent Articles
1.
Burrus C, McKinstry S, Kim N, Ozlu M, Santoki A, Fang F, et al.
Cell Rep
. 2020 Jan;
30(3):642-657.e6.
PMID: 31968243
Huntington's disease (HD) is caused by an autosomal dominant polyglutamine expansion mutation of Huntingtin (HTT). HD patients suffer from progressive motor, cognitive, and psychiatric impairments, along with significant degeneration of...
2.
McKinstry S, Karadeniz Y, Worthington A, Hayrapetyan V, Ozlu M, Serafin-Molina K, et al.
J Neurosci
. 2014 Jul;
34(28):9455-72.
PMID: 25009276
Huntington's disease (HD) is a neurodegenerative disease caused by the expansion of a poly-glutamine (poly-Q) stretch in the huntingtin (Htt) protein. Gain-of-function effects of mutant Htt have been extensively investigated...
3.
Wan Y, Ade K, Caffall Z, Ozlu M, Eroglu C, Feng G, et al.
Biol Psychiatry
. 2013 Feb;
75(8):623-30.
PMID: 23414593
Background: Synapse-associated protein 90/postsynaptic density protein 95-associated protein 3 (SAPAP3) is an excitatory postsynaptic protein implicated in the pathogenesis of obsessive-compulsive behaviors. In mice, genetic deletion of Sapap3 causes obsessive-compulsive...
4.
Kucukdereli H, Allen N, Lee A, Feng A, Ozlu M, Conatser L, et al.
Proc Natl Acad Sci U S A
. 2011 Jul;
108(32):E440-9.
PMID: 21788491
Astrocytes regulate synaptic connectivity in the CNS through secreted signals. Here we identified two astrocyte-secreted proteins, hevin and SPARC, as regulators of excitatory synaptogenesis in vitro and in vivo. Hevin...