Yoichiro Kamimura
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Explore the profile of Yoichiro Kamimura including associated specialties, affiliations and a list of published articles.
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31
Citations
1380
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Recent Articles
11.
Tanabe Y, Kamimura Y, Ueda M
J Cell Sci
. 2018 Nov;
131(23).
PMID: 30404836
In eukaryotic chemotaxis, parallel signaling pathways regulate the spatiotemporal pseudopod dynamics at the leading edge of a motile cell through the characteristic dynamics of an excitable system; however, differences in...
12.
Miyagawa T, Koteishi H, Kamimura Y, Miyanaga Y, Takeshita K, Nakagawa A, et al.
Nat Commun
. 2018 Nov;
9(1):4635.
PMID: 30401901
G protein interacting protein 1 (Gip1) binds and sequesters heterotrimeric G proteins in the cytosolic pool, thus regulating G protein-coupled receptor (GPCR) signalling for eukaryotic chemotaxis. Here, we report the...
13.
Kamimura Y, Miyanaga Y, Ueda M
Proc Natl Acad Sci U S A
. 2016 Apr;
113(16):4356-61.
PMID: 27044073
Chemotactic eukaryote cells can sense chemical gradients over a wide range of concentrations via heterotrimeric G-protein signaling; however, the underlying wide-range sensing mechanisms are only partially understood. Here we report...
14.
Gao R, Zhao S, Jiang X, Sun Y, Zhao S, Gao J, et al.
Sci Signal
. 2015 May;
8(378):ra50.
PMID: 26012633
Directional cell migration in an electric field, a phenomenon called galvanotaxis or electrotaxis, occurs in many types of cells, and may play an important role in wound healing and development....
15.
Gao R, Zhang X, Sun Y, Kamimura Y, Mogilner A, Devreotes P, et al.
Eukaryot Cell
. 2011 Jul;
10(9):1251-6.
PMID: 21743003
Many types of cells migrate directionally in direct current (DC) electric fields (EFs), a phenomenon termed galvanotaxis or electrotaxis. The directional sensing mechanisms responsible for this response to EFs, however,...
16.
Sld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast
Tanaka T, Umemori T, Endo S, Muramatsu S, Kanemaki M, Kamimura Y, et al.
EMBO J
. 2011 Apr;
30(10):2019-30.
PMID: 21487389
Genetic screening of yeast for sld (synthetic lethality with dpb11) mutations has identified replication proteins, including Sld2, -3, and -5, and clarified the molecular mechanisms underlying eukaryotic chromosomal DNA replication....
17.
Tang M, Iijima M, Kamimura Y, Chen L, Long Y, Devreotes P
Mol Biol Cell
. 2010 Dec;
22(4):437-47.
PMID: 21169559
By limiting phosphotidylinositol 3,4,5-triphosphate (PIP(3)) levels, tumor suppressor PTEN not only controls cell growth but also maintains cell polarity required for cytokinesis and chemotaxis. To identify the critical targets of...
18.
Cai H, Das S, Kamimura Y, Long Y, Parent C, Devreotes P
J Cell Biol
. 2010 Jul;
190(2):233-45.
PMID: 20660630
In chemotactic cells, G protein-coupled receptors activate Ras proteins, but it is unclear how Ras-associated pathways link extracellular signaling to cell migration. We show that, in Dictyostelium discoideum, activated forms...
19.
Muramatsu S, Hirai K, Tak Y, Kamimura Y, Araki H
Genes Dev
. 2010 Mar;
24(6):602-12.
PMID: 20231317
Eukaryotic chromosomal DNA replication requires cyclin-dependent kinase (CDK) activity. CDK phosphorylates two yeast replication proteins, Sld3 and Sld2, both of which bind to Dpb11 when phosphorylated. These phosphorylation-dependent interactions are...
20.
Kamimura Y, Devreotes P
J Biol Chem
. 2010 Jan;
285(11):7938-46.
PMID: 20075071
Chemotactic cells must sense shallow extracellular gradients and produce localized intracellular responses. We previously showed that the temporal and spatial activation of two protein kinase B (PKB) homologues, PkbA and...