Yohannes Tesfaigzi
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Explore the profile of Yohannes Tesfaigzi including associated specialties, affiliations and a list of published articles.
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143
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4036
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Recent Articles
1.
Ling F, Sahin A, Naranjo B, Aime S, Roth D, Tepho N, et al.
bioRxiv
. 2025 Jan;
PMID: 39868248
Mucus plays an integral role for the barrier function of many epithelial tissues. In the human airways, mucus is constantly secreted to capture inhaled microbes and pollutants and cleared away...
2.
Sun C, Tesfaigzi Y, Lee G, Chen Y, Weiss S, Ma K
J Allergy Clin Immunol
. 2024 Oct;
155(1):219-222.e1.
PMID: 39368553
Background: Previous randomized controlled trials have established the efficacy of dupilumab among patients with chronic obstructive pulmonary disease (COPD) treated with triple therapy over 52 weeks of follow-up. Objective: This...
3.
Yildirim A, Conlon T, Adcock I, Gosens R, Lehmann M, Kapellos T, et al.
Eur Respir J
. 2024 Sep;
64(3).
PMID: 39326903
No abstract available.
4.
Joseph J, Baby H, Quintero J, Kenney D, Mebratu Y, Bhatia E, et al.
Adv Mater
. 2024 Sep;
36(46):e2406348.
PMID: 39318086
Nasal sprays for pre-exposure prophylaxis against respiratory infections show limited protection (20-70%), largely due to their single mechanism of action-either neutralizing pathogens or blocking their entry at the nasal lining,...
5.
Parekh M, Adhikari Y, Deshpande N, Miller P, Sperling A, Tesfaigzi Y, et al.
Exp Eye Res
. 2024 Sep;
248:110089.
PMID: 39265717
Epidemiological studies show cigarette smoking enhances corneal endothelial dysfunction, but mechanisms remain unclear. Our study reveals that prolonged smoke exposure activates the aryl hydrocarbon receptor (AhR), increasing CYP1B1 expression and...
6.
Moll M, Pratte K, Debban C, Liu C, Belinsky S, Picchi M, et al.
Sci Rep
. 2024 Sep;
14(1):20618.
PMID: 39232179
Protein biomarkers are associated with mortality in cardiovascular disease, but their effect on predicting respiratory and all-cause mortality is not clear. We tested whether a protein risk score (protRS) can...
7.
Negasi Z, Nommi N, Liu C, Tesfaigzi Y
Am J Physiol Lung Cell Mol Physiol
. 2024 Feb;
326(4):L431-L439.
PMID: 38349118
Chronic obstructive pulmonary disease (COPD) is caused by cigarette smoke (CS) exposure but can often be progressive even in former smokers. Exposure of mice to CS for 22 wk causes...
8.
Zhai J, Voraphani N, Imboden M, Keidel D, Liu C, Stern D, et al.
J Allergy Clin Immunol
. 2024 Jan;
153(6):1692-1703.
PMID: 38253260
Background: Airflow limitation is a hallmark of chronic obstructive pulmonary disease, which can develop through different lung function trajectories across the life span. There is a need for longitudinal studies...
9.
Mebratu Y, Jones J, Liu C, Negasi Z, Rahman M, Rojas-Quintero J, et al.
J Clin Invest
. 2023 Dec;
134(4.
PMID: 38113109
Although chronic low-grade inflammation does not cause immediate clinical symptoms, over the longer term, it can enhance other insults or age-dependent damage to organ systems and thereby contribute to age-related...
10.
Divo M, Liu C, Polverino F, Castaldi P, Celli B, Tesfaigzi Y
Eur Respir J
. 2023 Sep;
62(3).
PMID: 37678951
Background: The lifetime risk of developing clinical COPD among smokers ranges from 13% to 22%. Identifying at-risk individuals who will develop overt disease in a reasonable timeframe may allow for...