Yiyun Lin
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Explore the profile of Yiyun Lin including associated specialties, affiliations and a list of published articles.
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40
Citations
878
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Recent Articles
1.
Moussa M, Khandelwal J, Wilson N, Malikayil K, Surasi D, Bathala T, et al.
J Immunother Cancer
. 2025 Feb;
13(2).
PMID: 39939142
Background: Nivolumab plus ipilimumab (nivo/ipi) is a standard of care first-line (1 L) therapy for patients with metastatic clear-cell renal cell carcinoma (ccRCC), but its role in patients with metastatic,...
2.
Zhai X, Lin D, Shen Y, Zhai N, Yu F, Zhang J, et al.
Front Oncol
. 2025 Jan;
14():1492571.
PMID: 39839794
Background: The carcinogenesis mechanism of early-stage lung cancer (ESLC) remains unclear. Microbial dysbiosis is closely related to tumor development. This study aimed to analyze the relationship between microbiota dysbiosis in...
3.
Lin Y, Wang J, Wang K, Bai S, Thennavan A, Wei R, et al.
Nature
. 2024 Nov;
636(8043):663-670.
PMID: 39567687
Aneuploid epithelial cells are common in breast cancer; however, their presence in normal breast tissues is not well understood. To address this question, we applied single-cell DNA sequencing to profile...
4.
Liu Y, Wu J, Najem H, Lin Y, Pang L, Khan F, et al.
J Clin Invest
. 2024 Oct;
134(22).
PMID: 39352749
Tumor-associated macrophages and microglia (TAMs) are critical for tumor progression and therapy resistance in glioblastoma (GBM), a type of incurable brain cancer. We previously identified lysyl oxidase (LOX) and olfactomedin...
5.
Wang K, Yan Y, Elgamal H, Li J, Tang C, Bai S, et al.
bioRxiv
. 2024 Sep;
PMID: 39314325
Understanding the impact of genetic alterations on epigenomic phenotypes during breast cancer progression is challenging with unimodal measurements. Here, we report wellDA-seq, the first high-genomic resolution, high-throughput method that can...
6.
Lin Y, Gao J, Zheng H, Guo Y, Liu Z, Sun T
Foot Ankle Int
. 2024 May;
45(8):824-832.
PMID: 38721810
Background: This study evaluates the outcomes of fibular intramedullary nails (IMNs) compared to traditional plates and screws (PS) in the surgical treatment of unstable ankle injuries in patients aged ≥65 ...
7.
LaBella K, Hsu W, Li J, Qi Y, Liu Y, Liu J, et al.
Dev Cell
. 2024 Apr;
59(11):1475-1486.e5.
PMID: 38574731
Telomere dynamics are linked to aging hallmarks, and age-associated telomere loss fuels the development of epithelial cancers. In Apc-mutant mice, the onset of DNA damage associated with telomere dysfunction has...
8.
Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu W, et al.
Nat Commun
. 2024 Mar;
15(1):1987.
PMID: 38443336
Abundant macrophage infiltration and altered tumor metabolism are two key hallmarks of glioblastoma. By screening a cluster of metabolic small-molecule compounds, we show that inhibiting glioblastoma cell glycolysis impairs macrophage...
9.
Lin D, Zhai X, Qi X, Zhou Q, Liu Y, Lin Y, et al.
J Transl Med
. 2024 Mar;
22(1):231.
PMID: 38433192
No abstract available.
10.
Alhalabi O, Wilson N, Xiao L, Lin Y, Khandelwal J, Moussa M, et al.
Eur Urol Oncol
. 2023 Oct;
6(6):611-620.
PMID: 37833193
Background: Neoadjuvant chemotherapy (neoCTX) has been recommended as the optimal strategy in surgically resectable neuroendocrine carcinoma (NEC) of the urinary tract (NEC-URO). Objective: To determine the systemic therapy regimen and...