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Y R Hsu

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Articles 27
Citations 146
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Recent Articles
1.
Hsu Y, Nybo R, Sullivan J, Costigan V, Spahr C, Wong C, et al.
Biochemistry . 1999 Feb; 38(8):2523-34. PMID: 10029547
Keratinocyte growth factor (KGF or FGF-7) is a member of the heparin binding fibroblast growth factor (FGF) family and is a paracrine mediator of proliferation and differentiation of a wide...
2.
Hsu Y, Hsu E, Katta V, Brankow D, Tseng J, Hu S, et al.
Protein Expr Purif . 1998 Apr; 12(2):189-200. PMID: 9518460
Keratinocyte growth factor (KGF) is a member of the fibroblast growth factor family that acts specifically on epithelial cells in a paracrine mode. We employed a mammalian expression system to...
3.
Hsu Y, Chang W, Mendiaz E, Hara S, Chow D, Mann M, et al.
Biochemistry . 1998 Mar; 37(8):2251-62. PMID: 9485371
During in vitro aging, deamidation of recombinant human stem cell factor produced in Escherichia. coli was detected by HPLC analysis and by the release of soluble ammonia. The deamidation rate...
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Hsu Y, Wu G, Mendiaz E, Syed R, Wypych J, Toso R, et al.
J Biol Chem . 1997 Mar; 272(10):6406-15. PMID: 9045664
Soluble Escherichia coli-derived recombinant human stem cell factor (rhSCF) forms a non-covalently associated dimer. We have determined a dimer association constant (Ka) of 2-4 x 10(8) M-1, using sedimentation equilibrium...
6.
Lu H, Hsu Y, Narhi L, Karkare S, Lin F
Protein Expr Purif . 1996 Sep; 8(2):227-37. PMID: 8812867
We report here the expression of recombinant human prokallikrein and kallikrein in engineered Chinese hamster ovary cells transfected with a human genomic gene encoding preprokallikrein. At high expression levels, recombinant...
7.
Lu H, Hsu Y, Lu L, Ruff D, Lyons D, Lin F
Protein Expr Purif . 1996 Sep; 8(2):215-26. PMID: 8812865
This report describes bacterial expression, isolation, and characterization of human tissue kallikrein recombinantly produced in Escherichia coli. Successful production of enzymatically active recombinant human kallikrein requires the following processes: expression,...
8.
Hsu Y, Narhi L, Spahr C, Langley K, Lu H
Protein Sci . 1996 Jun; 5(6):1165-73. PMID: 8762148
The effect of oxidation of the methionine residues of Escherichia coli-derived recombinant human stem cell factor (huSCF) to methionine sulfoxide on the structure and activity of SCF was examined. Oxidation...
9.
Lu H, Chang W, Mendiaz E, Mann M, Langley K, Hsu Y
Biochem J . 1995 Jan; 305 ( Pt 2):563-8. PMID: 7530446
In its native state, recombinant human-stem-cell-factor (SCF) dimer can spontaneously and rapidly undergo hybridization when two different SCF dimer species are incubated together. SCF species differing in molecular charge, e.g.,...
10.
Hsu Y, Chuang J, Huang C, Changchien C
Changgeng Yi Xue Za Zhi . 1994 Jun; 17(2):173-7. PMID: 8069743
Hydrometrocolpos is a rare congenital anomaly and serious life threatening condition in the newborn infant due to its long-term compression sequelae and associated congenital anomalies. Prenatal diagnosis of hydrometrocolpos by...