N Stebbing
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Explore the profile of N Stebbing including associated specialties, affiliations and a list of published articles.
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77
Citations
470
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Recent Articles
1.
Moochhala S, Renton K, Stebbing N
Biochem Pharmacol
. 1989 Feb;
38(3):439-47.
PMID: 2917006
A novel analogue of human alpha-interferon (IFN-alpha CON1) was tested for its ability to modify the hepatic cytochrome P-450-dependent mixed-function oxidase system in the hamster. This cloned interferon was derived...
2.
Fish E, Banerjee K, Stebbing N
J Interferon Res
. 1989 Feb;
9(1):97-114.
PMID: 2523943
Earlier studies showed that minor differences in primary structure among the interferon-alpha (IFN-alpha) protein family are reflected in their potency in selected biological assays. These studies have been extended and...
3.
Stevenson R, Stebbing N, Jones T, Carr K, Jones P, Hii C, et al.
Acta Endocrinol (Copenh)
. 1988 Apr;
117(4):457-62.
PMID: 3291525
hGH32-38 was tested to determine if the peptide could affect hepatic glucose production in the conscious dog under basal conditions (euglycemia) or if it could enhance glucose uptake when hyperglycemia...
4.
Fish E, Banerjee K, Arakawa T, Stebbing N
Drug Des Deliv
. 1988 Feb;
2(3):191-206.
PMID: 2855574
Structure/function relationships for human gamma interferon (IFN-gamma) were investigated using recombinant DNA-derived homologues produced in E. coli. The various biological effects examined were antiviral, growth inhibitory and 2-5A synthetase activities,...
5.
Pfeffer L, Stebbing N, Donner D
Proc Natl Acad Sci U S A
. 1987 May;
84(10):3249-53.
PMID: 2953024
Human Daudi lymphoblastoid cells, which are highly sensitive to the antiproliferative action of human leukocyte alpha-interferon (IFN-alpha), and IFN-resistant and IFN-sensitive Daudi subclones (Cl2 and Cl1, respectively), contain 2300 (Kd...
6.
Stevenson R, Stebbing N, Rudman C, Williams P, Cherrington A
Metabolism
. 1987 Apr;
36(4):400-4.
PMID: 3550377
Human growth hormone (hGH, 22 K) has an acute insulinlike effect not observed with the 20 K variant form of hGH that lacks amino acids 32 to 46 (deletion peptide,...
7.
Arakawa T, Hsu Y, Toth E, Stebbing N
J Interferon Res
. 1987 Feb;
7(1):103-5.
PMID: 3035033
No abstract available.
8.
Trousdale M, Robin J, Stebbing N
Curr Eye Res
. 1987 Jan;
6(1):269-72.
PMID: 3030648
Because of reported differences in potency, recombinant DNA-derived human alpha interferons (IFNs) were reevaluated for use against acute Herpes Simplex Virus type 1 (HSV-1) infection of the rabbit eye. The...
9.
Arakawa T, Hsu Y, Chang D, Stebbing N, Altrock B
J Interferon Res
. 1986 Dec;
6(6):687-95.
PMID: 3106525
Structural properties and activity of recombinant human interferon-gamma (IFN-gamma) purified from Chinese hamster ovary (CHO) cells or a natural source were determined and compared with those of Escherichia coli-derived IFN-gamma....
10.
Hsu Y, Ferguson B, Narachi M, RICHARDS R, Stabinsky Y, Alton N, et al.
J Interferon Res
. 1986 Dec;
6(6):663-70.
PMID: 3106523
We have prepared interferon-gamma (IFN-gamma) analogs to study the structural role of particular amino acids in relation to their effects on antiviral activity. Three IFN-gamma analogs were prepared on the...