Xue-Jun Jin
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Explore the profile of Xue-Jun Jin including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
204
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Recent Articles
1.
Gao Y, Li M, Wang D, Jin S, Ma X, Jin X, et al.
Chem Biol Drug Des
. 2024 Dec;
104(6):e70024.
PMID: 39702874
Nuclear factor κB (NF-κB) is a key inducible transcription factor that controls a large number of genes involved in inflammatory and immune processes. The entire inflammation-mediated process uses NF-κB as...
2.
Ma X, Li M, Jin K, Han Z, Gao Y, Jin X, et al.
Chem Biodivers
. 2024 Aug;
21(12):e202401542.
PMID: 39193815
The hypoxia-inducible factor-1α (HIF-1α) pathway has been implicated in tumor angiogenesis, growth, and metastasis. Therefore, the inhibition of this pathway is an important therapeutic target for cancer. Thiazole derivatives have...
3.
Zhao Y, Qin Y, Hu X, Chen X, Jiang Y, Jin X, et al.
Front Pharmacol
. 2024 May;
15:1406127.
PMID: 38720779
: (G. lucidum, Lingzhi) is a medicinal and edible homologous traditional Chinese medicine that is used to treat various diseases, including Alzheimer's disease and mood disorders. We previously reported that...
4.
Qin Y, Zhao Y, Hu X, Chen X, Jiang Y, Jin X, et al.
Front Pharmacol
. 2024 May;
15:1390294.
PMID: 38720773
() has long been listed as a premium tonic that can be used to improve restlessness, insomnia, and forgetfulness. We previously reported that a rat model of sporadic Alzheimer's disease...
5.
Zhang L, Li M, Wang D, Jin X, Chen F, Piao H
Molecules
. 2022 Nov;
27(22).
PMID: 36432026
(1) Background: Nuclear factor κB (NF-κB) is an important transcriptional regulator that regulates the inflammatory pathway and plays a key role in cellular inflammatory and immune responses. The presence of...
6.
Guo H, Xing Y, Sun Y, Liu C, Xu Q, Shang F, et al.
J Ginseng Res
. 2022 Oct;
46(6):738-749.
PMID: 36312731
Background: Ginseng possesses antitumor effects, and ginsenosides are considered to be one of its main active chemical components. Ginsenosides can further be hydrolyzed to generate secondary saponins, and 20()-panaxotriol is...
7.
Zhang H, Yuan S, Meng H, Hou X, Li J, Xue J, et al.
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955628
Inflammatory bowel disease (IBD) is a chronic, relapsing disease that severely affects patients' quality of life. The exact cause of IBD is uncertain, but current studies suggest that abnormal activation...
8.
Xue Y, Li M, Jin X, Zheng C, Piao H
J Enzyme Inhib Med Chem
. 2021 Jan;
36(1):295-306.
PMID: 33404277
Five series of novel carbazole derivatives containing an aminoguanidine, dihydrotriazine, thiosemicarbazide, semicarbazide or isonicotinic moiety were designed, synthesised and evaluated for their antimicrobial activities. Most of the compounds exhibited potent...
9.
Wang D, Li Y, Zhang L, Lv L, Zhao Y, Jin X, et al.
Bioorg Med Chem Lett
. 2020 Nov;
30(24):127652.
PMID: 33130293
Hypoxia-inducible factor 1α (HIF-1α) is a known regulator of tumor cell proliferation, migration, and angiogenesis. The presence of a high concentration of HIF-1α is positively correlated with the severity of...
10.
Xu X, Jin L, Jiang T, Lu Y, Aosai F, Piao H, et al.
J Ginseng Res
. 2020 Sep;
44(5):704-716.
PMID: 32913400
Background: Ginsenoside Rh2 (GRh2) is a characterized component in red ginseng widely used in Korea and China. GRh2 exhibits a wide range of pharmacological activities, such as anti-inflammatory, antioxidant, and...