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Xiaotan T Qiao

Explore the profile of Xiaotan T Qiao including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 1054
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Recent Articles
1.
Li L, Hao X, Qin J, Tang W, He F, Smith A, et al.
Gastroenterology . 2014 Jan; 146(4):1108-18. PMID: 24397969
Background & Aims: CD44s is a surface marker of tumor-initiating cells (TICs); high tumor levels correlate with metastasis and recurrence, as well as poor outcomes for patients. Monoclonal antibodies against...
2.
Li L, Tang W, Wu X, Karnak D, Meng X, Thompson R, et al.
Clin Cancer Res . 2013 Oct; 19(24):6703-15. PMID: 24132924
Purpose: Signal transducer and activator of transcription 3 (STAT3) plays a critical role in initiation and progression of pancreatic cancer. However, therapeutically targeting STAT3 has failed clinically. We previously identified...
3.
Saqui-Salces M, Keeley T, Grosse A, Qiao X, El-Zaatari M, Gumucio D, et al.
Histochem Cell Biol . 2011 Jun; 136(2):191-204. PMID: 21688022
Epithelial tuft cells are named after their characteristic microtubule bundles located at the cell apex where these are exposed to the luminal environment. As such, tuft cells are found in...
4.
Qiao X, Gumucio D
J Gastroenterol . 2011 Jun; 46(7):855-65. PMID: 21626457
Gastric stem and progenitor cells (GPC) play key roles in the homeostatic renewal of gastric glands and are instrumental in epithelial repair after injury. Until very recently, the existence of...
5.
Li X, Udager A, Hu C, Qiao X, Richards N, Gumucio D
Dev Dyn . 2009 Oct; 238(12):3205-17. PMID: 19877272
In the adult mouse, distinct morphological and transcriptional differences separate stomach from intestinal epithelium. Remarkably, the epithelial boundary between these two organs is literally one cell thick. This discrete junction...
6.
Qiao X, Ziel J, McKimpson W, Madison B, Todisco A, Merchant J, et al.
Gastroenterology . 2007 Dec; 133(6):1989-98. PMID: 18054570
Background & Aims: Epithelial stem cells in the stomach are responsible for constant renewal of the epithelium through generation of multiple gastric cell lineages that populate the gastric glands. However,...
7.
Madison B, Braunstein K, Kuizon E, Portman K, Qiao X, Gumucio D
Development . 2004 Dec; 132(2):279-89. PMID: 15590741
Morphological development of the small intestinal mucosa involves the stepwise remodeling of a smooth-surfaced endodermal tube to form finger-like luminal projections (villi) and flask-shaped invaginations (crypts). These remodeling processes are...
8.
Rieder G, Tessier A, Qiao X, Madison B, Gumucio D, Merchant J
J Biol Chem . 2004 Dec; 280(6):4906-12. PMID: 15576363
Chronic Helicobacter pylori infection results in serious sequelae, including atrophy, intestinal metaplasia, and gastric cancer. Intestinal metaplasia in the stomach is defined by the presence of intestine-like cells expressing enterocyte-specific...
9.
Madison B, Dunbar L, Qiao X, Braunstein K, Braunstein E, Gumucio D
J Biol Chem . 2002 Jun; 277(36):33275-83. PMID: 12065599
Villin, an actin bundling protein found in the apical brush border of absorptive tissues, is one of the first structural genes to be transcriptionally activated in the embryonic intestinal endoderm....
10.
Braunstein E, Qiao X, Madison B, Pinson K, Dunbar L, Gumucio D
Dev Dyn . 2002 May; 224(1):90-102. PMID: 11984877
In the adult gastrointestinal tract, the morphologic borders between esophagus and stomach and between stomach and small intestine are literally one cell thick. The patterning mechanisms that underlie the development...