Juanita L Merchant
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Explore the profile of Juanita L Merchant including associated specialties, affiliations and a list of published articles.
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132
Citations
2791
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Recent Articles
1.
Zinkeng A, Taylor F, Cheong S, Song H, Merchant J
Cell Mol Gastroenterol Hepatol
. 2024 Nov;
19(2):101425.
PMID: 39510499
The onset of colorectal cancer (CRC) in patients younger than 50 continues to rapidly increase. This study highlights the epidemiologic changes, risk factors, clinical characteristics, and molecular profiles prevalent in...
2.
Arshad J, Rao A, Repp M, Rao R, Wu C, Merchant J
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38474232
Gastrointestinal cancers represent one of the more challenging cancers to treat. Current strategies to cure and control gastrointestinal (GI) cancers like surgery, radiation, chemotherapy, and immunotherapy have met with limited...
3.
Knapp T, Lima N, Daigle N, Duan S, Merchant J, Sawyer T
J Biomed Opt
. 2024 Jan;
29(1):016007.
PMID: 38264434
Significance: Multiphoton microscopy (MPM) is a useful biomedical imaging tool for its ability to probe labeled and unlabeled depth-resolved tissue biomarkers at high resolution. Automated MPM tile scanning allows for...
4.
Duan S, Sawyer T, Witten B, Song H, Else T, Merchant J
J Pathol
. 2024 Jan;
262(3):362-376.
PMID: 38229586
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are heterogeneous malignancies that arise from complex cellular interactions within the tissue microenvironment. Here, we sought to decipher tumor-derived signals from the surrounding microenvironment by applying...
5.
Chopp L, Zhu X, Gao Y, Nie J, Singh J, Kumar P, et al.
Sci Immunol
. 2023 Nov;
8(89):eadi9066.
PMID: 37948511
How CD4 lineage gene expression is initiated in differentiating thymocytes remains poorly understood. Here, we show that the paralog transcription factors Zfp281 and Zfp148 control both this process and cytokine...
6.
Daigle N, Duan S, Song H, Lima N, Sontz R, Merchant J, et al.
J Biomed Opt
. 2023 Sep;
28(9):096004.
PMID: 37711357
Significance: Lineage tracing using fluorescent reporters is a common tool for monitoring the expression of genes and transcription factors in stem cell populations and their progeny. The zinc-binding protein 89...
7.
Hibdon E, Keeley T, Merchant J, Samuelson L
Am J Physiol Gastrointest Liver Physiol
. 2023 Sep;
325(5):G458-G470.
PMID: 37698169
Notch signaling regulates gastrointestinal stem cell proliferation and differentiation yet Notch-regulated transcriptional effectors of gastric epithelial cell differentiation are poorly understood. Here we tested the role of the bHLH transcription...
8.
Slomka B, Duan S, Knapp T, Lima N, Sontz R, Merchant J, et al.
Front Photon
. 2023 Sep;
3.
PMID: 37691859
Gastrointestinal cancers continue to account for a disproportionately large percentage of annual cancer deaths in the US. Advancements in miniature imaging technology combined with a need for precise and thorough...
9.
Duan S, Sheriff S, Elvis-Offiah U, Witten B, Sawyer T, Sundaresan S, et al.
Cancer Res Commun
. 2023 Jul;
3(7):1318-1334.
PMID: 37492626
Significance: We examined the function of somatic and germline mutations and a variant of sequenced from gastroenteropancreatic NETs. We report that these mutations and variant promote tumor cell growth and...
10.
Ding L, Sheriff S, Sontz R, Merchant J
Front Immunol
. 2023 Jun;
14:1139391.
PMID: 37334372
Introduction: MDSCs express SCHLAFEN 4 (SLFN4) in -infected stomachs coincident with spasmolytic polypeptide-expressing metaplasia (SPEM), a precursor of gastric cancer. We aimed to characterize SLFN4 cell identity and the role...