Xiaohui Zha
Overview
Explore the profile of Xiaohui Zha including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
573
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0
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Recent Articles
1.
Andersen C, Presseau J, Shea B, Marti M, McCoy M, Fernie G, et al.
Transl Stroke Res
. 2024 Jul;
16(1):49-78.
PMID: 38997598
Aneurysmal subarachnoid haemorrhage (aSAH) is a devastating condition with high mortality and morbidity. The outcome measures used in aSAH clinical research vary making it challenging to compare and combine different...
2.
Salloum Z, Dauner K, Li Y, Verma N, Valdivieso-Gonzalez D, Almendro-Vedia V, et al.
Elife
. 2024 Apr;
13.
PMID: 38602170
Statins are known to be anti-inflammatory, but the mechanism remains poorly understood. Here, we show that macrophages, either treated with statin in vitro or from statin-treated mice, have reduced cholesterol...
3.
Niznick N, Saigle V, Marti M, Laframboise J, Zha X, Andersen C, et al.
Neurology
. 2023 Feb;
100(15):e1565-e1573.
PMID: 36750387
Background And Objectives: There is significant heterogeneity in the reporting of outcome measures in aneurysmal subarachnoid hemorrhage (aSAH) research. The modified Rankin scale (mRS) is the most commonly reported functional...
4.
Saiioum Z, Dauner K, Li Y, Verma N, Almendro-Vedia V, Valdivieso Gonzalez D, et al.
bioRxiv
. 2023 Jan;
PMID: 36711703
Stains are known to be anti-inflammatory, but the mechanism remains poorly understood. Here we show that macrophages, either treated with statin in vitro or from statin-treated mice, have reduced cholesterol...
5.
Nakka K, Hachmer S, Mokhtari Z, Kovac R, Bandukwala H, Bernard C, et al.
Science
. 2022 Aug;
377(6606):666-669.
PMID: 35926054
Muscle stem cells (MuSCs) reside in a specialized niche that ensures their regenerative capacity. Although we know that innate immune cells infiltrate the niche in response to injury, it remains...
6.
Singh R, Haka A, Bhardwaj P, Zha X, Maxfield F
Arterioscler Thromb Vasc Biol
. 2018 Dec;
39(2):137-149.
PMID: 30580573
Objective- During atherosclerosis, LDLs (low-density lipoproteins) accumulate in the arteries, where they become modified, aggregated, and retained. Such deposits of aggregated LDL (agLDL) can be recognized by macrophages, which attempt...
7.
Comment on 'Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol'
Courtney K, Fung K, Maxfield F, Fairn G, Zha X
Elife
. 2018 Nov;
7.
PMID: 30422112
The plasma membrane in mammalian cells is rich in cholesterol, but how the cholesterol is partitioned between the two leaflets of the plasma membrane remains a matter of debate. Recently,...
8.
Eid W, Dauner K, Courtney K, Gagnon A, Parks R, Sorisky A, et al.
Proc Natl Acad Sci U S A
. 2017 Jul;
114(30):7999-8004.
PMID: 28696297
mTORC1 is known to activate sterol regulatory element-binding proteins (SREBPs) including SREBP-2, a master regulator of cholesterol synthesis. Through incompletely understood mechanisms, activated mTORC1 triggers translocation of SREBP-2, an endoplasmic...
9.
Dauner K, Eid W, Raghupathy R, Presley J, Zha X
J Biol Chem
. 2017 Feb;
292(14):5737-5747.
PMID: 28196862
The plasma membrane of mammalian cells undergoes constitutive endocytosis, endocytic sorting, and recycling, which delivers nutrients to the lysosomes. The receptors, along with membrane lipids, are normally returned to the...
10.
Ferrier A, De Repentigny Y, Lynch-Godrei A, Gibeault S, Eid W, Kuo D, et al.
Autophagy
. 2015 Jun;
11(7):1025-36.
PMID: 26043942
A homozygous mutation in the DST (dystonin) gene causes a newly identified lethal form of hereditary sensory and autonomic neuropathy in humans (HSAN-VI). DST loss of function similarly leads to...