Lauralyn McIntyre
Overview
Explore the profile of Lauralyn McIntyre including associated specialties, affiliations and a list of published articles.
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Articles
142
Citations
6386
Followers
0
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Recent Articles
1.
Takaoka A, Johnstone J, Lauzier F, Heels-Ansdell D, Davis M, Zytaruk N, et al.
Trials
. 2024 Dec;
25(1):851.
PMID: 39731129
Background: Understanding site-related factors that influence enrolment within multicenter randomized controlled trials (RCT) may help reduce trial delays and cost over-runs and prevent early trial discontinuation. In this analysis of...
2.
English S, Delaney A, Fergusson D, Chasse M, Turgeon A, Lauzier F, et al.
N Engl J Med
. 2024 Dec;
392(11):1079-1088.
PMID: 39655786
Background: The effect of a liberal red-cell transfusion strategy as compared with a restrictive strategy in patients during the critical care period after an aneurysmal subarachnoid hemorrhage is unclear. Methods:...
3.
Daneman N, Rishu A, Pinto R, Rogers B, Rogers B, Shehabi Y, et al.
N Engl J Med
. 2024 Nov;
392(11):1065-1078.
PMID: 39565030
Background: Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. Methods: In a multicenter, noninferiority trial, we...
4.
Terrett L, Reszel J, Ameri S, Turgeon A, McIntyre L, English S
Neurocrit Care
. 2024 Oct;
PMID: 39402427
In aneurysmal subarachnoid hemorrhage, rebleeding prior to securing the culprit aneurysm leads to significant morbidity and mortality. Elevated blood pressure has been identified as a possible risk factor. In this...
5.
OHearn K, Menon K, Albrecht L, Amrein K, Britz-McKibbin P, Cayouette F, et al.
Trials
. 2024 Sep;
25(1):619.
PMID: 39300483
Background: The rate of vitamin D deficiency (VDD) in critically ill children worldwide has been estimated at 50%. These children are at risk of multiple organ dysfunction, chronic morbidity, and...
6.
Andersen C, Presseau J, Shea B, Marti M, McCoy M, Fernie G, et al.
Transl Stroke Res
. 2024 Jul;
16(1):49-78.
PMID: 38997598
Aneurysmal subarachnoid haemorrhage (aSAH) is a devastating condition with high mortality and morbidity. The outcome measures used in aSAH clinical research vary making it challenging to compare and combine different...
7.
Cook D, Taneja S, Krewulak K, Zytaruk N, Menon K, Fowler R, et al.
JAMA Netw Open
. 2024 Jul;
7(7):e2420458.
PMID: 38995645
Importance: The COVID-19 pandemic created unprecedented challenges for clinical trials worldwide, threatening premature closure and trial integrity. Every phase of research operations was affected, often requiring modifications to protocol design...
8.
Terrett L, McIntyre L, OKelly C, Ramsay T, Turgeon A, English S
Neurocrit Care
. 2024 Jun;
41(3):893-902.
PMID: 38862709
Background: In aneurysmal subarachnoid hemorrhage (aSAH), rebleeding of the culprit aneurysm is associated with significant morbidity and mortality. Blood pressure reduction to specific target levels, with the goal of preventing...
9.
Hum C, Tahir U, Mei S, Champagne J, Fergusson D, Lalu M, et al.
Stem Cells Transl Med
. 2024 Feb;
13(4):346-361.
PMID: 38381583
Background: In preclinical studies, mesenchymal stromal cells (MSCs), including umbilical cord-derived MSCs (UC-MSCs), demonstrate the ability to modulate numerous pathophysiological processes related to sepsis; however, a systematic synthesis of the...
10.
Terrett L, McIntyre L, Turgeon A, English S
Neurocrit Care
. 2023 Aug;
39(1):91-103.
PMID: 37634181
Anemia is very common in aneurysmal subarachnoid hemorrhage (aSAH), with approximately half of the aSAH patient population developing moderate anemia during their hospital stay. The available evidence (both physiologic and...