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Kiran Nakka

Explore the profile of Kiran Nakka including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 326
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Recent Articles
1.
Salloum Z, Dauner K, Li Y, Verma N, Valdivieso-Gonzalez D, Almendro-Vedia V, et al.
Elife . 2024 Apr; 13. PMID: 38602170
Statins are known to be anti-inflammatory, but the mechanism remains poorly understood. Here, we show that macrophages, either treated with statin in vitro or from statin-treated mice, have reduced cholesterol...
2.
Saiioum Z, Dauner K, Li Y, Verma N, Almendro-Vedia V, Valdivieso Gonzalez D, et al.
bioRxiv . 2023 Jan; PMID: 36711703
Stains are known to be anti-inflammatory, but the mechanism remains poorly understood. Here we show that macrophages, either treated with statin in vitro or from statin-treated mice, have reduced cholesterol...
3.
Collins E, Galipeau Y, Arnold C, Bosveld C, Heiskanen A, Keeshan A, et al.
BMJ Open . 2023 Jan; 12(9):e062187. PMID: 36691221
Purpose: To investigate the robustness and longevity of SARS-CoV-2 immune responses conferred by natural infection and vaccination among priority populations such as immunocompromised individuals and people with post-acute sequelae of...
4.
Nakka K, Hachmer S, Mokhtari Z, Kovac R, Bandukwala H, Bernard C, et al.
Science . 2022 Aug; 377(6606):666-669. PMID: 35926054
Muscle stem cells (MuSCs) reside in a specialized niche that ensures their regenerative capacity. Although we know that innate immune cells infiltrate the niche in response to injury, it remains...
5.
Anand S, Arnold C, Bangdiwala S, Bolotin S, Bowdish D, Chanchlani R, et al.
CMAJ Open . 2022 Jul; 10(3):E599-E609. PMID: 35790229
Background: Early in the COVID-19 pandemic, the South Asian community in the Greater Toronto Area (GTA) was identified as having risk factors for exposure and specific barriers to accessing testing...
6.
Li Y, Nakka K, Olender T, Gingras-Gelinas P, Wong M, Robinson D, et al.
STAR Protoc . 2021 Sep; 2(3):100751. PMID: 34467227
Muscle stem cells (MuSCs) are a rare stem cell population that provides myofibers with a remarkable capacity to regenerate after tissue injury. Here, we have adapted the Cleavage Under Target...
7.
Robinson D, Ritso M, Nelson G, Mokhtari Z, Nakka K, Bandukwala H, et al.
Dev Cell . 2021 Mar; 56(7):1014-1029.e7. PMID: 33735618
Negative elongation factor (NELF) is a critical transcriptional regulator that stabilizes paused RNA polymerase to permit rapid gene expression changes in response to environmental cues. Although NELF is essential for...
8.
Nakka K, Kovac R, Wong M, Dilworth F
Dev Cell . 2020 Jun; 53(6):623-625. PMID: 32574590
Molecular signatures defining quiescence in muscle satellite cells (mSCs) remain enigmatic. In this issue of Developmental Cell, Yue et al. adapted an in vivo fixation approach to isolate dormant mSCs...
9.
Asare-Werehene M, Nakka K, Reunov A, Chiu C, Lee W, Abedini M, et al.
Oncogene . 2019 Nov; 39(7):1600-1616. PMID: 31700155
Ovarian cancer (OVCA) is the most lethal gynecological cancer, due predominantly to late presentation, high recurrence rate and common chemoresistance development. The expression of the actin-associated protein cytosolic gelsolin (GSN)...
10.
Wu Q, Heidenreich D, Zhou S, Ackloo S, Kramer A, Nakka K, et al.
Nat Commun . 2019 Apr; 10(1):1915. PMID: 31015424
Bromodomains (BRDs) are conserved protein interaction modules which recognize (read) acetyl-lysine modifications, however their role(s) in regulating cellular states and their potential as targets for the development of targeted treatment...