Alpha 2.0
Login Register
» Authors » William Blanco-Bose

William Blanco-Bose

Explore the profile of William Blanco-Bose including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 1413
Followers 0
Related Specialties
General Medicine
Nutritional Sciences
Biology
Top 10 Co-Authors
Chris Rinsch
Patrick Aebischer
Anurag Singh
Penelope A Andreux
Johan Auwerx
Davide DAmico
Andreas Trumpp
Hong Wu
Richard C van der Wath
Ernesto Bockamp
Published In
Hum Gene Ther
Food Chem Toxicol
Cell Rep Med
Cell
Nat Metab
Affiliations
Soon will be listed here.
Recent Articles
1.
Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults
Singh A, DAmico D, Andreux P, Fouassier A, Blanco-Bose W, Evans M, et al.
Cell Rep Med . 2022 May; 3(5):100633. PMID: 35584623
Targeting mitophagy to activate the recycling of faulty mitochondria during aging is a strategy to mitigate muscle decline. We present results from a randomized, placebo-controlled trial in middle-aged adults where...
2.
Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population
Singh A, DAmico D, Andreux P, DunnGalvin G, Kern T, Blanco-Bose W, et al.
Eur J Clin Nutr . 2021 Jun; 76(2):297-308. PMID: 34117375
Background: Urolithin A (UA) is produced by gut microflora from foods rich in ellagitannins. UA has been shown to improve mitochondrial health preclinically and in humans. Not everyone has a...
3.
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans
Andreux P, Blanco-Bose W, Ryu D, Burdet F, Ibberson M, Aebischer P, et al.
Nat Metab . 2020 Jul; 1(6):595-603. PMID: 32694802
Urolithin A (UA) is a natural dietary, microflora-derived metabolite shown to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging. Here, we report the...
4.
Safety assessment of Urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid
Heilman J, Andreux P, Tran N, Rinsch C, Blanco-Bose W
Food Chem Toxicol . 2017 Aug; 108(Pt A):289-297. PMID: 28757461
Urolithins are metabolites produced in the gut following consumption of ellagitannins and ellagic acid rich foods such as pomegranates, nuts and certain berries. Urolithin A (UA) is one of the...
5.
Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization
Tesio M, Oser G, Baccelli I, Blanco-Bose W, Wu H, Gothert J, et al.
J Exp Med . 2013 Oct; 210(11):2337-49. PMID: 24127490
The phosphatase and tumor suppressor PTEN inhibits the phosphoinositol-3-kinase (PI3K) signaling pathway and plays a key role in cell growth, proliferation, survival, and migration. Pten conditional deletion using MxCre or...
6.
Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
Wilson A, Laurenti E, Oser G, van der Wath R, Blanco-Bose W, Jaworski M, et al.
Cell . 2008 Dec; 135(6):1118-29. PMID: 19062086
Bone marrow hematopoietic stem cells (HSCs) are crucial to maintain lifelong production of all blood cells. Although HSCs divide infrequently, it is thought that the entire HSC pool turns over...
7.
Lentiviral-mediated RNA interference
Abbas-Terki T, Blanco-Bose W, Deglon N, Pralong W, Aebischer P
Hum Gene Ther . 2003 Jan; 13(18):2197-201. PMID: 12542850
RNA interference (RNAi) is a form of posttranscriptional gene silencing mediated by short double-stranded RNA, known as small interfering RNA (siRNA). These siRNAs are capable of binding to a specific...