Wiley J Youngs
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Explore the profile of Wiley J Youngs including associated specialties, affiliations and a list of published articles.
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61
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768
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Recent Articles
1.
Johnson N, Xue Y, Panzner M, Youngs W, Tessier C
Inorg Chem
. 2024 Oct;
63(43):20281-20285.
PMID: 39418475
In this study, the reaction between phosphazene superbases and a chlorophosphazene trimer ([PClN]) has been investigated. In this room temperature reaction, the phosphazene superbase (MeN)PN(MeN)P═NEt, commonly known as PEt, was...
2.
Southerland M, DeBord M, Johnson N, Crabtree S, Alexander N, Stromyer M, et al.
Bioorg Med Chem
. 2020 Dec;
30:115893.
PMID: 33333447
A series of novel bis-imidazolium salts was synthesized, characterized, and evaluated in vitro against a panel of non-small cell lung cancer (NSCLC) cells. Two imidazolium cores were connected with alkyl...
3.
Stromyer M, Southerland M, Satyal U, Sikder R, Weader D, Baughman J, et al.
Eur J Med Chem
. 2019 Nov;
185:111832.
PMID: 31718944
Imidazolium salts have shown great promise as anticancer materials. A new imidazolium salt (TPP1), with a triphenylphosphonium substituent, has been synthesized and evaluated for in vitro and in vivo cytotoxicity...
4.
Emhoff K, Balaraman L, Simpson S, Stromyer M, Kalil H, Beemiller J, et al.
ACS Omega
. 2019 Aug;
3(11):16021-16027.
PMID: 31458240
Removal of chloride from CoCl with TlPF in acetonitrile, followed by addition of excess nitrosobenzene, yielded the eight-coordinate cobalt(II) complex salt [Co{Ph(O)NN(O)Ph}](PF), shown by single-crystal X-ray analysis to have a...
5.
Shah P, Shah K, Smolen J, Tagaev J, Torrealba J, Zhou L, et al.
Sci Rep
. 2018 Apr;
8(1):6376.
PMID: 29686296
To address the escalating problem of antimicrobial resistance and the dwindling antimicrobial pipeline, we have developed a library of novel aerosolizable silver-based antimicrobials, particularly for the treatment of pulmonary infections....
6.
Johnson N, Southerland M, Youngs W
Molecules
. 2017 Jul;
22(8).
PMID: 28749425
Because of their great structural diversity and multitude of chemical properties, N-heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently, NHCs have been utilized as carrier...
7.
DeBord M, Southerland M, Wagers P, Tiemann K, Robishaw N, Whiddon K, et al.
Bioorg Med Chem Lett
. 2017 Jan;
27(4):764-775.
PMID: 28126518
Alkyl- and N,N'-bisnaphthyl-substituted imidazolium salts were tested in vitro for their anti-cancer activity against four non-small cell lung cancer cell lines (NCI-H460, NCI-H1975, HCC827, A549). All compounds had potent anticancer...
8.
DeBord M, Wagers P, Crabtree S, Tessier C, Panzner M, Youngs W
Bioorg Med Chem Lett
. 2016 Dec;
27(2):196-202.
PMID: 27939175
A series of C-alkyl substituted N,N'-bis(arylmethyl)imidazolium salts were synthesized, characterized, and tested for their in vitro anti-cancer activity against multiple non-small cell lung cancer cell lines by our group and...
9.
Shelton K, DeBord M, Wagers P, Southerland M, Williams T, Robishaw N, et al.
Bioorg Med Chem
. 2016 Nov;
25(1):421-439.
PMID: 27876249
A series of N,N'-bis(arylmethyl)benzimidazolium salts have been synthesized and evaluated for their in vitro anti-cancer activity against select non-small cell lung cancer cell lines to create a structure activity relationship...
10.
Tun Z, Heston A, Panzner M, Scionti V, Medvetz D, Wright B, et al.
Inorg Chem
. 2016 Mar;
55(7):3283-93.
PMID: 26974866
Irrespective of the order of the addition of reagents, the reactions of [PCl2N]3 with MX3 (MX3 = AlCl3, AlBr3, GaCl3) in the presence of water or gaseous HX give the...