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W R Bensch

Explore the profile of W R Bensch including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 112
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Recent Articles
1.
Kauffman R, Bean J, Fahey K, Cullinan G, Cox D, Bensch W
J Cardiovasc Pharmacol . 2000 Oct; 36(4):459-65. PMID: 11026646
The effects of raloxifene and 17alpha-ethinyl estradiol (EE2) on intimal thickening in response to balloon injury were tested in male and ovariectomized female rats. In male rats, oral raloxifene and...
2.
Bensch W, Gadski R, Bean J, Beavers L, Schmidt R, Perry D, et al.
J Pharmacol Exp Ther . 1999 Mar; 289(1):85-92. PMID: 10086991
The action of LY295427 [(3alpha,4alpha, 5alpha)-4-(2-propenylcholestan-3-ol)], a compound that derepresses low-density lipoprotein receptor (LDL-R) expression in a cell-based model, was examined in hamsters. It was found that the compound does...
3.
Kauffman R, Bensch W, Roudebush R, Cole H, Bean J, Phillips D, et al.
J Pharmacol Exp Ther . 1997 Jan; 280(1):146-53. PMID: 8996192
After once-daily oral dosing in ovariectomized rats, raloxifene (LY139481) hydrochloride produced dose- and time-dependent reductions in serum cholesterol and high-density lipoprotein-cholesterol. Paired-feeding studies demonstrated that effects of raloxifene on serum...
4.
Lin H, Rampersaud A, Archer R, Pawlak J, Beavers L, Schmidt R, et al.
J Med Chem . 1995 Jan; 38(2):277-88. PMID: 7830271
A new series of sterols was synthesized and tested in a CHO cell-based LDL receptor/luciferase (LDLR/Luc) assay to investigate the capability of derepressing the transcription of LDL receptor promoter in...
5.
Evans G, Bensch W, Apelgren L, Bailey D, Kauffman R, Bumol T, et al.
J Lipid Res . 1994 Sep; 35(9):1634-45. PMID: 7806977
The effects of cholesteryl ester transfer protein (CETP) inhibition on the serum lipoprotein profile in both normocholesterolemic and hypercholesterolemic hamsters has been determined following subcutaneous injection of 12.5 mg/kg of...
6.
Black L, Sato M, Rowley E, Magee D, Bekele A, Williams D, et al.
J Clin Invest . 1994 Jan; 93(1):63-9. PMID: 8282823
There is a medical need for an agent with the positive effects of estrogen on bone and the cardiovascular system, but without the negative effects on reproductive tissue. Raloxifene (LY139481...
7.
Rodwell V, Bensch W
Methods Enzymol . 1981 Jan; 71 Pt C:480-6. PMID: 7278665
No abstract available.
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Bensch W, Rodwell V
J Biol Chem . 1970 Aug; 245(15):3755-62. PMID: 4321764
No abstract available.