Alpha 2.0
Login Register
» Authors » J S Bean

J S Bean

Explore the profile of J S Bean including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 25
Followers 0
Related Specialties
Pharmacology
Biochemistry
Biology
Top 10 Co-Authors
R F Kauffman
W R Bensch
G J Cullinan
W E Bloomquist
A L Glasebrook
A P Breau
A Williams
R A Archer
D A Cox
R J Schmidt
Published In
J Pharmacol Exp Ther
Life Sci
J Cardiovasc Pharmacol
Vet Pathol
Affiliations
Soon will be listed here.
Recent Articles
1.
Raloxifene and estrogen inhibit neointimal thickening after balloon injury in the carotid artery of male and ovariectomized female rats
Kauffman R, Bean J, Fahey K, Cullinan G, Cox D, Bensch W
J Cardiovasc Pharmacol . 2000 Oct; 36(4):459-65. PMID: 11026646
The effects of raloxifene and 17alpha-ethinyl estradiol (EE2) on intimal thickening in response to balloon injury were tested in male and ovariectomized female rats. In male rats, oral raloxifene and...
2.
Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters
Bensch W, Gadski R, Bean J, Beavers L, Schmidt R, Perry D, et al.
J Pharmacol Exp Ther . 1999 Mar; 289(1):85-92. PMID: 10086991
The action of LY295427 [(3alpha,4alpha, 5alpha)-4-(2-propenylcholestan-3-ol)], a compound that derepresses low-density lipoprotein receptor (LDL-R) expression in a cell-based model, was examined in hamsters. It was found that the compound does...
3.
Hypocholesterolemic activity of raloxifene (LY139481): pharmacological characterization as a selective estrogen receptor modulator
Kauffman R, Bensch W, Roudebush R, Cole H, Bean J, Phillips D, et al.
J Pharmacol Exp Ther . 1997 Jan; 280(1):146-53. PMID: 8996192
After once-daily oral dosing in ovariectomized rats, raloxifene (LY139481) hydrochloride produced dose- and time-dependent reductions in serum cholesterol and high-density lipoprotein-cholesterol. Paired-feeding studies demonstrated that effects of raloxifene on serum...
4.
Inhibition of vascular smooth muscle cell proliferation and arterial intimal thickening by a novel antiproliferative naphthopyran
Wiernicki T, Bean J, Dell C, Williams A, Wood D, Kauffman R, et al.
J Pharmacol Exp Ther . 1996 Sep; 278(3):1452-9. PMID: 8819533
Smooth muscle cell proliferation plays an important role in neointimal thickening after vascular injury and may contribute to restenosis after angioplasty. Development of suitable pharmacological agents modulating smooth muscle cell...
5.
Vascular serotonin 5-hydroxytryptamine2 receptor blockade by LY215840: lack of effect upon neointima formation in balloon-injured rat carotid arteries
Kauffman R, Bean J, Bloomquist W, Cohen M
J Pharmacol Exp Ther . 1993 Jul; 266(1):450-5. PMID: 8331571
5-Hydroxytryptamine (5-HT) is mitogenic for vascular smooth muscle cells, an effect that may result from 5-HT2 receptor activation. After arterial balloon injury, platelet-derived products including 5-HT are delivered to the...
6.
Passive role of articular chondrocytes in the pathogenesis of acute meniscectomy-induced cartilage degeneration
Bendele A, Bean J, Hulman J
Vet Pathol . 1991 May; 28(3):207-15. PMID: 1858253
The importance of viable articular chondrocytes and enzymes or factors from surgically traumatized synovium in the pathogenesis of acute meniscectomy-induced cartilage degeneration was examined in guinea pigs (nine groups of...
7.
Losartan, a nonpeptide angiotensin II (Ang II) receptor antagonist, inhibits neointima formation following balloon injury to rat carotid arteries
Kauffman R, Bean J, Zimmerman K, Brown R, Steinberg M
Life Sci . 1991 Jan; 49(25):PL223-8. PMID: 1745100
Angiotensin-converting enzyme inhibitors have been shown to inhibit intimal thickening following balloon catheterization of rat carotid arteries. To assess the role of the renin-angiotensin pathway and the angiotensin type-I (AT1)...