Vinodkumar B Pillai
Overview
Explore the profile of Vinodkumar B Pillai including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
2227
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Recent Articles
1.
Samant S, Pillai V, Gupta M
JCSM Rapid Commun
. 2021 Jul;
4(1):40-56.
PMID: 34212132
Background: During cancer cachexia, cytokines released from tumour cells can alter body's metabolism, which can lead to onset of this disease process. Biological basis of cachexia is multifactorial; hence, it...
2.
Pillai V, Samant S, Hund S, Gupta M, Gupta M
Aging (Albany NY)
. 2021 May;
13(9):12334-12358.
PMID: 33934090
Sirtuins have been shown to regulate the aging process. We have previously demonstrated that Sirt6 blocks the pressure overload-induced cardiac hypertrophy in mice. Here, we show that Sirt6 can also...
3.
Pillai V, Gupta M
Am J Physiol Endocrinol Metab
. 2020 Dec;
320(3):E399-E414.
PMID: 33308014
The ability to ward off pathogens with minimal damage to the host determines the immune system's robustness. Multiple factors, including pathogen processing, identification, secretion of mediator and effector molecules, and...
4.
Kanwal A, Pillai V, Samant S, Gupta M, Gupta M
FASEB J
. 2019 Jul;
33(10):10872-10888.
PMID: 31318577
Sirtuins (Sirts) are implicated in regulating a myriad of biologic functions ranging from cell growth and metabolism to longevity. Here, we show that nuclear Sirt, Sirt6, and mitochondrial Sirt, Sirt3,...
5.
Samant S, Pillai V, Gupta M
Can J Physiol Pharmacol
. 2018 Nov;
97(4):235-245.
PMID: 30407871
Many chronic diseases are associated with unintentional loss of body weight, which is termed "cachexia". Cachexia is a complex multifactorial syndrome associated with the underlying primary disease, and characterized by...
6.
Samant S, Kanwal A, Pillai V, Bao R, Gupta M
Sci Rep
. 2017 Sep;
7(1):11877.
PMID: 28928419
Muscle wasting, also known as cachexia, is associated with many chronic diseases, which worsens prognosis of primary illness leading to enhanced mortality. Molecular basis of this metabolic syndrome is not...
7.
Pillai V, Kanwal A, Fang Y, Sharp W, Samant S, Arbiser J, et al.
Oncotarget
. 2017 Apr;
8(21):34082-34098.
PMID: 28423723
Doxorubicin is the chemotherapeutic drug of choice for a wide variety of cancers, and cardiotoxicity is one of the major side effects of doxorubicin treatment. One of the main cellular...
8.
Bindu S, Pillai V, Kanwal A, Samant S, Mutlu G, Verdin E, et al.
Am J Physiol Lung Cell Mol Physiol
. 2016 Nov;
312(1):L68-L78.
PMID: 27815257
Myofibroblast differentiation is a key process in the pathogenesis of fibrotic diseases. Transforming growth factor-β (TGF-β) is a powerful inducer of myofibroblast differentiation and is implicated in pathogenesis of tissue...
9.
Bindu S, Pillai V, Gupta M
Trends Endocrinol Metab
. 2016 May;
27(8):563-573.
PMID: 27210897
Cardiovascular diseases (CVDs) are expanding at an alarming rate and people's propensity to develop them increases with age. Growing evidence indicates that sirtuins play a pivotal role in regulating a...
10.
Pillai V, Bindu S, Sharp W, Fang Y, Kim G, Gupta M, et al.
Am J Physiol Heart Circ Physiol
. 2016 Feb;
310(8):H962-72.
PMID: 26873966
Doxorubicin (Doxo) is a chemotherapeutic drug widely used to treat variety of cancers. One of the most serious side effects of Doxo is its dose-dependent and delayed toxicity to the...