Vinodkumar B Pillai
Overview
Explore the profile of Vinodkumar B Pillai including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
26
Citations
2227
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Sundaresan N, Bindu S, Pillai V, Samant S, Pan Y, Huang J, et al.
Mol Cell Biol
. 2015 Dec;
36(5):678-92.
PMID: 26667039
Tissue fibrosis is a major cause of organ dysfunction during chronic diseases and aging. A critical step in this process is transforming growth factor β1 (TGF-β1)-mediated transformation of fibroblasts into...
12.
Samant S, Pillai V, Sundaresan N, Shroff S, Gupta M
J Biol Chem
. 2015 Apr;
290(25):15559-15569.
PMID: 25911107
Reversible lysine acetylation is a widespread post-translational modification controlling the activity of proteins in different subcellular compartments. We previously demonstrated that a class II histone deacetylase (HDAC), HDAC4, and a...
13.
Pillai V, Samant S, Sundaresan N, Raghuraman H, Kim G, Bonner M, et al.
Nat Commun
. 2015 Apr;
6:6656.
PMID: 25871545
Honokiol (HKL) is a natural biphenolic compound derived from the bark of magnolia trees with anti-inflammatory, anti-oxidative, anti-tumour and neuroprotective properties. Here we show that HKL blocks agonist-induced and pressure...
14.
Pillai V, Sundaresan N, Gupta M
Circ Res
. 2014 Jan;
114(2):368-78.
PMID: 24436432
Cardiac hypertrophy is a multifactorial disease characterized by multiple molecular alterations. One of these alterations is change in the activity of Akt, which plays a central role in regulating a...
15.
Samant S, Zhang H, Hong Z, Pillai V, Sundaresan N, Wolfgeher D, et al.
Mol Cell Biol
. 2013 Dec;
34(5):807-19.
PMID: 24344202
Mitochondrial morphology is regulated by the balance between two counteracting mitochondrial processes of fusion and fission. There is significant evidence suggesting a stringent association between morphology and bioenergetics of mitochondria....
16.
Pillai V, Sundaresan N, Kim G, Samant S, Moreno-Vinasco L, Garcia J, et al.
Am J Physiol Heart Circ Physiol
. 2012 Dec;
304(3):H415-26.
PMID: 23203961
Nicotinamide phosphoribosyltransferase (Nampt) is an important coenzyme involved in cellular redox reactions. Inside the cell, Nampt (iNampt) functions as a rate-limiting enzyme in the NAD salvage pathway, and outside the...
17.
The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun
Sundaresan N, Vasudevan P, Zhong L, Kim G, Samant S, Parekh V, et al.
Nat Med
. 2012 Oct;
18(11):1643-50.
PMID: 23086477
Abnormal activation of insulin-like growth factor (IGF)-Akt signaling is implicated in the development of various diseases, including heart failure. However, the molecular mechanisms that regulate activation of this signaling pathway...
18.
Sundaresan N, Pillai V, Wolfgeher D, Samant S, Vasudevan P, Parekh V, et al.
Sci Signal
. 2011 Jul;
4(182):ra46.
PMID: 21775285
Signaling through the kinase Akt regulates many biological functions. Akt is activated during growth factor stimulation through a process that requires binding of Akt to phosphatidylinositol 3,4,5-trisphosphate (PIP(3)), which promotes...
19.
Pillai V, Sundaresan N, Samant S, Wolfgeher D, Trivedi C, Gupta M
Mol Cell Biol
. 2011 Mar;
31(11):2349-63.
PMID: 21444723
Like phosphorylation, acetylation of lysine residues within a protein is considered a biologically relevant modification that controls the activity of target proteins. During stress of cells, massive protein acetylation takes...
20.
Sundaresan N, Pillai V, Gupta M
J Mol Cell Cardiol
. 2011 Feb;
51(4):614-8.
PMID: 21276800
Calorie restriction is considered to be the best environmental intervention providing health benefits to mammals. The underlying mechanism of this intervention seems to be controlled by a group of NAD-dependent...