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Vincent Stroobant

Explore the profile of Vincent Stroobant including associated specialties, affiliations and a list of published articles. Areas
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Articles 83
Citations 3668
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Recent Articles
1.
McAuliffe J, Panetti S, Steffke E, Wicki A, Pereira-Almeida V, Noblecourt L, et al.
J Immunother Cancer . 2024 Oct; 12(10). PMID: 39384196
Background: Melanoma antigen gene (MAGE)-type antigens are promising targets for cancer immunotherapy as they are expressed in cancer cells but not in normal tissues, except for male germline cells. The...
2.
Paquay S, Duraffourd J, Bury M, Heremans I, Caligiore F, Gerin I, et al.
Cell Mol Life Sci . 2024 Aug; 81(1):367. PMID: 39174697
Hydroxylated fatty acids are important intermediates in lipid metabolism and signaling. Surprisingly, the metabolism of 4-hydroxy fatty acids remains largely unexplored. We found that both ACAD10 and ACAD11 unite two...
3.
Dorrazehi G, Winkle M, Desmet M, Stroobant V, Tanriver G, Degand H, et al.
Sci Rep . 2024 Jun; 14(1):13999. PMID: 38890528
Penicillin binding proteins (PBPs) are involved in biosynthesis, remodeling and recycling of peptidoglycan (PG) in bacteria. PBP-A from Thermosynechococcus elongatus belongs to a cyanobacterial family of enzymes sharing close structural...
4.
Solvay M, Holfelder P, Klaessens S, Pilotte L, Stroobant V, Lamy J, et al.
J Immunother Cancer . 2023 Jun; 11(6). PMID: 37344101
Background: Indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan-dioxygenase (TDO) are enzymes catabolizing the essential amino acid tryptophan into kynurenine. Expression of these enzymes is frequently observed in advanced-stage cancers and is...
5.
Klaessens S, Stroobant V, De Plaen E, Van den Eynde B
Front Mol Biosci . 2022 Oct; 9:897929. PMID: 36188218
Tryptophan is an essential amino acid, which is not only a building block for protein synthesis, but also a precursor for the biosynthesis of co-enzymes and neuromodulators, such as NAD/NADP(H),...
6.
Ferrari V, Stroobant V, Abi Habib J, Naulaerts S, Van den Eynde B, Vigneron N
J Immunol . 2022 Jun; 208(12):2817-2828. PMID: 35688464
By tying peptide fragments originally distant in parental proteins, the proteasome can generate spliced peptides that are recognized by CTL. This occurs by transpeptidation involving a peptide-acyl-enzyme intermediate and another...
7.
Sorgeloos F, Peeters M, Hayashi Y, Borghese F, Capelli N, Drappier M, et al.
Proc Natl Acad Sci U S A . 2022 Jan; 119(5). PMID: 35091472
Microbes have been coevolving with their host for millions of years, exploiting host resources to their own benefit. We show that viral and bacterial pathogens convergently evolved to hijack cellular...
8.
Heremans I, Caligiore F, Gerin I, Bury M, Lutz M, Graff J, et al.
Proc Natl Acad Sci U S A . 2022 Jan; 119(4). PMID: 35046029
Cells are continuously exposed to potentially dangerous compounds. Progressive accumulation of damage is suspected to contribute to neurodegenerative diseases and aging, but the molecular identity of the damage remains largely...
9.
Kozlova A, Thabault L, Dauguet N, Deskeuvre M, Stroobant V, Pilotte L, et al.
Eur J Med Chem . 2021 Oct; 227:113892. PMID: 34678572
Selenium is an underexplored element that can be used for bioisosteric replacement of lower molecular weight chalcogens such as oxygen and sulfur. More studies regarding the impact of selenium substitution...
10.
Kozlova A, Thabault L, Liberelle M, Klaessens S, Prevost J, Mathieu C, et al.
J Med Chem . 2021 Aug; 64(17):13096. PMID: 34436896
No abstract available.