» Authors » Vanessa Ruiz-Bonilla

Vanessa Ruiz-Bonilla

Explore the profile of Vanessa Ruiz-Bonilla including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 11
Citations 2009
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Garcia-Prat L, Perdiguero E, Alonso-Martin S, DellOrso S, Ravichandran S, Brooks S, et al.
Nat Cell Biol . 2020 Oct; 22(11):1307-1318. PMID: 33106654
Tissue regeneration declines with ageing but little is known about whether this arises from changes in stem-cell heterogeneity. Here, in homeostatic skeletal muscle, we identify two quiescent stem-cell states distinguished...
2.
Solanas G, Peixoto F, Perdiguero E, Jardi M, Ruiz-Bonilla V, Datta D, et al.
Cell . 2017 Aug; 170(4):678-692.e20. PMID: 28802040
Normal homeostatic functions of adult stem cells have rhythmic daily oscillations that are believed to become arrhythmic during aging. Unexpectedly, we find that aged mice remain behaviorally circadian and that...
3.
Sebastian D, Sorianello E, Segales J, Irazoki A, Ruiz-Bonilla V, Sala D, et al.
EMBO J . 2016 Jun; 35(15):1677-93. PMID: 27334614
Mitochondrial dysfunction and accumulation of damaged mitochondria are considered major contributors to aging. However, the molecular mechanisms responsible for these mitochondrial alterations remain unknown. Here, we demonstrate that mitofusin 2...
4.
Garcia-Prat L, Martinez-Vicente M, Perdiguero E, Ortet L, Rodriguez-Ubreva J, Rebollo E, et al.
Nature . 2016 Jan; 529(7584):37-42. PMID: 26738589
During ageing, muscle stem-cell regenerative function declines. At advanced geriatric age, this decline is maximal owing to transition from a normal quiescence into an irreversible senescence state. How satellite cells...
5.
Sousa-Victor P, Gutarra S, Garcia-Prat L, Rodriguez-Ubreva J, Ortet L, Ruiz-Bonilla V, et al.
Nature . 2014 Feb; 506(7488):316-21. PMID: 24522534
Regeneration of skeletal muscle depends on a population of adult stem cells (satellite cells) that remain quiescent throughout life. Satellite cell regenerative functions decline with ageing. Here we report that...
6.
Vidal B, Ardite E, Suelves M, Ruiz-Bonilla V, Janue A, Flick M, et al.
Hum Mol Genet . 2012 Mar; 21(9):1989-2004. PMID: 22381526
In Duchenne muscular dystrophy (DMD), a persistently altered and reorganizing extracellular matrix (ECM) within inflamed muscle promotes damage and dysfunction. However, the molecular determinants of the ECM that mediate inflammatory...
7.
Perdiguero E, Sousa-Victor P, Ruiz-Bonilla V, Jardi M, Caelles C, Serrano A, et al.
J Cell Biol . 2011 Oct; 195(2):307-22. PMID: 21987635
Repair of damaged tissue requires the coordinated action of inflammatory and tissue-specific cells to restore homeostasis, but the underlying regulatory mechanisms are poorly understood. In this paper, we report new...
8.
Ruiz-Bonilla V, Perdiguero E, Gresh L, Serrano A, Zamora M, Sousa-Victor P, et al.
Cell Cycle . 2008 Jul; 7(14):2208-14. PMID: 18641461
Adult skeletal muscle is a very stable tissue containing a small population of myofiber-associated quiescent satellite cells compared with late embryonic/neonatal skeletal muscle, which contains highly proliferating myoblasts and small...
9.
Vidal B, Serrano A, Tjwa M, Suelves M, Ardite E, De Mori R, et al.
Genes Dev . 2008 Jul; 22(13):1747-52. PMID: 18593877
In the fatal degenerative Duchenne muscular dystrophy (DMD), skeletal muscle is progressively replaced by fibrotic tissue. Here, we show that fibrinogen accumulates in dystrophic muscles of DMD patients and mdx...
10.
Perdiguero E, Ruiz-Bonilla V, Serrano A, Munoz-Canoves P
Cell Cycle . 2007 May; 6(11):1298-303. PMID: 17534150
The regulation of skeletal muscle formation (myogenesis) is essential for normal development as well as in pathological conditions such as muscular dystrophies and inflammatory myopathies. Findings published over the past...