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Antonio L Serrano

Explore the profile of Antonio L Serrano including associated specialties, affiliations and a list of published articles. Areas
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Articles 53
Citations 4579
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Recent Articles
1.
Roig-Soriano J, Edo A, Verdes S, Martin-Alonso C, Sanchez-de-Diego C, Rodriguez-Estevez L, et al.
Mol Ther . 2025 Feb; PMID: 39988871
Aging is a major risk factor for pathologies including sarcopenia, osteoporosis, and cognitive decline, which bring suffering, disability, and elevated economic and social costs. Therefore, new therapies are needed to...
2.
Grima-Terren M, Campanario S, Ramirez-Pardo I, Cisneros A, Hong X, Perdiguero E, et al.
Mol Aspects Med . 2024 Sep; 100:101319. PMID: 39312874
Sarcopenia is a progressive muscle wasting disorder that severely impacts the quality of life of elderly individuals. Although the natural aging process primarily causes sarcopenia, it can develop in response...
3.
Kumar A, Vaca-Dempere M, Mortimer T, Deryagin O, Smith J, Petrus P, et al.
Science . 2024 May; 384(6695):563-572. PMID: 38696572
A molecular clock network is crucial for daily physiology and maintaining organismal health. We examined the interactions and importance of intratissue clock networks in muscle tissue maintenance. In arrhythmic mice...
4.
Lai Y, Ramirez-Pardo I, Isern J, An J, Perdiguero E, Serrano A, et al.
Nature . 2024 Apr; 629(8010):154-164. PMID: 38649488
Muscle atrophy and functional decline (sarcopenia) are common manifestations of frailty and are critical contributors to morbidity and mortality in older people. Deciphering the molecular mechanisms underlying sarcopenia has major...
5.
Moiseeva V, Cisneros A, Sica V, Deryagin O, Lai Y, Jung S, et al.
Nature . 2023 Feb; 614(7949):E45. PMID: 36747036
No abstract available.
6.
Moiseeva V, Cisneros A, Sica V, Deryagin O, Lai Y, Jung S, et al.
Nature . 2022 Dec; 613(7942):169-178. PMID: 36544018
Tissue regeneration requires coordination between resident stem cells and local niche cells. Here we identify that senescent cells are integral components of the skeletal muscle regenerative niche that repress regeneration...
7.
Hong X, Isern J, Campanario S, Perdiguero E, Ramirez-Pardo I, Segales J, et al.
Cell Stem Cell . 2022 Oct; 29(10):1506-1508. PMID: 36206734
No abstract available.
8.
Hong X, Isern J, Campanario S, Perdiguero E, Ramirez-Pardo I, Segales J, et al.
Cell Stem Cell . 2022 Aug; 29(9):1298-1314.e10. PMID: 35998641
Skeletal muscle regeneration depends on the correct expansion of resident quiescent stem cells (satellite cells), a process that becomes less efficient with aging. Here, we show that mitochondrial dynamics are...
9.
Moiseeva V, Cisneros A, Cobos A, Tarrega A, Onate C, Perdiguero E, et al.
FEBS J . 2022 Jul; 290(5):1161-1185. PMID: 35811491
Cellular senescence is a state of irreversible cell cycle arrest that often emerges after tissue damage and in age-related diseases. Through the production of a multicomponent secretory phenotype (SASP), senescent...
10.
Kharraz Y, Lukesova V, Serrano A, Davison A, Munoz-Canoves P
Cytometry A . 2022 May; 101(10):862-876. PMID: 35608022
Autofluorescence (AF) is an intrinsic characteristic of cells caused by the presence of fluorescent biological compounds within the cell; these can include structural proteins (e.g., collagen and elastin), cellular organelles,...