Pedro Sousa-Victor
Overview
Explore the profile of Pedro Sousa-Victor including associated specialties, affiliations and a list of published articles.
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28
Citations
1857
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Recent Articles
1.
Sousa N, Bica M, Bras M, Sousa A, Antunes I, Encarnacao I, et al.
Cell Rep
. 2024 Nov;
43(11):114975.
PMID: 39541212
Age-related alterations in the immune system are starting to emerge as key contributors to impairments found in aged organs. A decline in regenerative capacity is a hallmark of tissue aging;...
2.
Sousa N, Bras M, Antunes I, Lindholm P, Neves J, Sousa-Victor P
Nat Aging
. 2023 Apr;
3(5):585-599.
PMID: 37118549
Age-related decline in skeletal muscle regenerative capacity is multifactorial, yet the contribution of immune dysfunction to regenerative failure is unknown. Macrophages are essential for effective debris clearance and muscle stem...
3.
Sousa-Victor P, Garcia-Prat L, Munoz-Canoves P
Nat Rev Mol Cell Biol
. 2021 Oct;
23(3):204-226.
PMID: 34663964
Skeletal muscle contains a designated population of adult stem cells, called satellite cells, which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically and usually by asymmetric cell division...
4.
Sousa-Victor P, Neves J, Munoz-Canoves P
Mech Ageing Dev
. 2020 Apr;
188:111246.
PMID: 32311419
Aging is characterized by the functional and regenerative decline of tissues and organs. This regenerative decline is a consequence of the numerical and functional loss of adult stem cells, which...
5.
Segales J, Perdiguero E, Serrano A, Sousa-Victor P, Ortet L, Jardi M, et al.
Nat Commun
. 2020 Jan;
11(1):189.
PMID: 31929511
A unique property of skeletal muscle is its ability to adapt its mass to changes in activity. Inactivity, as in disuse or aging, causes atrophy, the loss of muscle mass...
6.
Munoz-Canoves P, Neves J, Sousa-Victor P
FEBS J
. 2019 Dec;
287(3):406-416.
PMID: 31854082
Aging is characterized by the progressive dysfunction of most tissues and organs, which has been linked to the regenerative decline of their resident stem cells over time. Skeletal muscle provides...
7.
Neves J, Sousa-Victor P
FEBS J
. 2019 Sep;
287(1):43-52.
PMID: 31529582
Aging is accompanied by a decline in physiological integrity and a loss of regenerative capacity in many tissues. The development of interventions that prevent or reverse age-related disease requires a...
8.
Korzelius J, Azami S, Ronnen-Oron T, Koch P, Baldauf M, Meier E, et al.
Nat Commun
. 2019 Sep;
10(1):4123.
PMID: 31511511
In adult epithelial stem cell lineages, the precise differentiation of daughter cells is critical to maintain tissue homeostasis. Notch signaling controls the choice between absorptive and entero-endocrine cell differentiation in...
9.
Sousa-Victor P, Neves J, Cedron-Craft W, Ventura P, Liao C, Riley R, et al.
Nat Metab
. 2019 Sep;
1(2):276-290.
PMID: 31489403
Aging is accompanied by altered intercellular communication, deregulated metabolic function, and inflammation. Interventions that restore a youthful state delay or reverse these processes, prompting the search for systemic regulators of...
10.
Sousa-Victor P, Jasper H, Neves J
Front Physiol
. 2018 Dec;
9:1629.
PMID: 30515104
Regeneration is an important process in multicellular organisms, responsible for homeostatic renewal and repair of different organs after injury. Immune cell activation is observed at early stages of the regenerative...