Valentin Gogonea
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Explore the profile of Valentin Gogonea including associated specialties, affiliations and a list of published articles.
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50
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1542
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Recent Articles
1.
Xue Y, Salmon C, Gogonea V
Front Chem
. 2024 Dec;
12:1486175.
PMID: 39737223
Quenching peroxynitrite (a reactive oxidant species) is a vital process in biological systems and environmental chemistry as it maintains redox balance and mitigates damaging effects in living cells and the...
2.
Saha P, Gogonea V, Sweet W, Mohan M, Singh K, Anderson J, et al.
Nat Commun
. 2024 Aug;
15(1):6696.
PMID: 39107277
Allosteric modulation is a central mechanism for metabolic regulation but has yet to be described for a gut microbiota-host interaction. Phenylacetylglutamine (PAGln), a gut microbiota-derived metabolite, has previously been clinically...
3.
Zin I, China A, Khan K, Nag J, Vasu K, Deshpande G, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(30):e2303642121.
PMID: 39012819
Glutamyl-prolyl-tRNA synthetase (EPRS1) is a bifunctional aminoacyl-tRNA-synthetase (aaRS) essential for decoding the genetic code. EPRS1 resides, with seven other aaRSs and three noncatalytic proteins, in the cytoplasmic multi-tRNA synthetase complex...
4.
Khan D, Ramachandiran I, Vasu K, China A, Khan K, Cumbo F, et al.
Nat Commun
. 2024 May;
15(1):4284.
PMID: 38769304
Hypomyelinating leukodystrophy (HLD) is an autosomal recessive disorder characterized by defective central nervous system myelination. Exome sequencing of two siblings with severe cognitive and motor impairment and progressive hypomyelination characteristic...
5.
Choucair I, Mallela D, Hilser J, Hartiala J, Nemet I, Gogonea V, et al.
Diabetes
. 2024 May;
73(8):1215-1228.
PMID: 38701355
Article Highlights:
6.
Banerjee R, Hohe R, Cao S, Jung B, Horak A, Ramachandiran I, et al.
Front Physiol
. 2024 May;
15():1371096.
PMID: 38694206
Introduction: The Aster-C protein (encoded by the gene) is an endoplasmic reticulum (ER) resident protein that has been reported to transport cholesterol from the plasma membrane to the ER. Although...
7.
Salmon C, Xue Y, Gogonea V
Inorg Chem
. 2023 Nov;
62(48):19412-19420.
PMID: 37971807
Although the synthesis of chlorophosphazene polymers has been explored for more than 100 years, the shortest yet most illusive monomer, ClP═NH, has never been isolated and fully characterized. Here we...
8.
Zhu Y, Dwidar M, Nemet I, Buffa J, Sangwan N, Li X, et al.
Cell Host Microbe
. 2022 Dec;
31(1):18-32.e9.
PMID: 36549300
Recent studies show gut microbiota-dependent metabolism of dietary phenylalanine into phenylacetic acid (PAA) is critical in phenylacetylglutamine (PAGln) production, a metabolite linked to atherosclerotic cardiovascular disease (ASCVD). Accordingly, microbial enzymes...
9.
Khan K, Long B, Gogonea V, Deshpande G, Vasu K, Fox P
Proc Natl Acad Sci U S A
. 2022 Aug;
119(36):e2205669119.
PMID: 36037331
Amino acid ligation to cognate transfer RNAs (tRNAs) is catalyzed by aminoacyl-tRNA synthetases (aaRSs)-essential interpreters of the genetic code during translation. Mammalian cells harbor 20 cytoplasmic aaRSs, out of which...
10.
Malaeb H, Choucair I, Wang Z, Li X, Li L, Boyd W, et al.
Redox Biol
. 2022 Jul;
55:102401.
PMID: 35870340
Background: Hydrogen sulfide (HS), a gaseous signaling molecule that impacts multiple physiological processes including aging, is produced via select mammalian enzymes and enteric sulfur-reducing bacteria. HS research is limited by...