Krishnendu Khan
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Explore the profile of Krishnendu Khan including associated specialties, affiliations and a list of published articles.
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20
Citations
127
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Recent Articles
1.
Zin I, China A, Khan K, Nag J, Vasu K, Deshpande G, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(30):e2303642121.
PMID: 39012819
Glutamyl-prolyl-tRNA synthetase (EPRS1) is a bifunctional aminoacyl-tRNA-synthetase (aaRS) essential for decoding the genetic code. EPRS1 resides, with seven other aaRSs and three noncatalytic proteins, in the cytoplasmic multi-tRNA synthetase complex...
2.
Mondal S, Nagendra L, Chowdhury A, Palui R, Biswas S, Mukherjee D, et al.
Indian J Endocrinol Metab
. 2024 Jun;
28(2):145-152.
PMID: 38911113
Introduction: Infants born preterm, with low birth weight (LBW), or with perinatal stress are at high risk for neonatal hypoglycemia. Low cortisol levels have also been demonstrated in this group...
3.
Khan D, Ramachandiran I, Vasu K, China A, Khan K, Cumbo F, et al.
Nat Commun
. 2024 May;
15(1):4284.
PMID: 38769304
Hypomyelinating leukodystrophy (HLD) is an autosomal recessive disorder characterized by defective central nervous system myelination. Exome sequencing of two siblings with severe cognitive and motor impairment and progressive hypomyelination characteristic...
4.
Vasu K, Ramachandiran I, Chechi A, Khan K, Khan D, Kaufman R, et al.
RNA Biol
. 2023 Sep;
20(1):737-749.
PMID: 37702393
Adiponectin, an adipocyte-specific secretory protein encoded by the gene has a causal role in insulin resistance. Anti-diabetic drugs increase plasma adiponectin by a poorly understood, post-transcriptional mechanism enhancing insulin sensitivity....
5.
Khan D, Terenzi F, Liu G, Ghosh P, Ye F, Nguyen K, et al.
Nat Commun
. 2023 Jun;
14(1):3385.
PMID: 37296097
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, generates multiple protein-coding, subgenomic RNAs (sgRNAs) from a longer genomic RNA, all bearing identical termini with poorly understood...
6.
Khan K, Fox P
Bioessays
. 2023 Mar;
45(5):e2300024.
PMID: 36916749
Complexes of two or more proteins form many, if not most, of the intracellular "machines" that execute physical and chemical work, and transmit information. Complexes can form from stochastic post-translational...
7.
Khan K, Long B, Gogonea V, Deshpande G, Vasu K, Fox P
Proc Natl Acad Sci U S A
. 2022 Aug;
119(36):e2205669119.
PMID: 36037331
Amino acid ligation to cognate transfer RNAs (tRNAs) is catalyzed by aminoacyl-tRNA synthetases (aaRSs)-essential interpreters of the genetic code during translation. Mammalian cells harbor 20 cytoplasmic aaRSs, out of which...
8.
Dawson J, Smith I, Martin W, Khan K, Cheng F, Eng C
Protein Sci
. 2022 Apr;
31(5):e4308.
PMID: 35481646
The Phosphatase and TENsin homolog deleted on chromosome 10 (PTEN) is a chief regulator of a variety of cellular processes including cell proliferation, migration, growth, and death. It is also...
9.
Khan K, Baleanu-Gogonea C, Willard B, Gogonea V, Fox P
STAR Protoc
. 2022 Mar;
3(1):101201.
PMID: 35284842
Despite recent advances in structural determination of individual proteins, elucidating the 3-dimensional architecture of large, multiprotein complexes remains challenging, partly because of issues related to structural integrity during purification. Here,...
10.
Khan K, Gogonea V, Fox P
Transl Oncol
. 2022 Mar;
19:101392.
PMID: 35278792
In mammalian cells, 20 aminoacyl-tRNA synthetases (AARS) catalyze the ligation of amino acids to their cognate tRNAs to generate aminoacylated-tRNAs. In higher eukaryotes, 9 of the 20 AARSs, along with...