Val Millar
Overview
Explore the profile of Val Millar including associated specialties, affiliations and a list of published articles.
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20
Citations
354
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0
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Recent Articles
1.
Bleloch J, Lu S, Khan S, Serala K, Seraia E, Millar V, et al.
Cancer Med
. 2024 Oct;
13(19):e70303.
PMID: 39403898
Background: The highly homologous T-box transcription factors TBX2 and TBX3 are critical for embryonic development, and their overexpression in postnatal tissues contributes to a wide range of malignancies, including melanoma...
2.
Dombi E, Marinaki T, Spingardi P, Millar V, Hadjichristou N, Carver J, et al.
Front Cell Dev Biol
. 2024 Apr;
12:1260496.
PMID: 38665433
In mitochondrial DNA (mtDNA) depletion syndrome (MDS), patients cannot maintain sufficient mtDNA for their energy needs. MDS presentations range from infantile encephalopathy with hepatopathy (Alpers syndrome) to adult chronic progressive...
3.
Perez-Diaz N, Hoffman E, Clements J, Cruickshank R, Doherty A, Ebner D, et al.
Front Toxicol
. 2023 Jul;
5:1177586.
PMID: 37469456
approaches are an essential tool in screening for toxicity of new chemicals, products and therapeutics. To increase the reproducibility and human relevance of these assessments, it is advocated to remove...
4.
Rodriguez-Berriguete G, Ranzani M, Prevo R, Puliyadi R, Machado N, Bolland H, et al.
Clin Cancer Res
. 2023 Jan;
29(8):1631-1642.
PMID: 36689546
Purpose: DNA polymerase theta (Polθ, encoded by the POLQ gene) is a DNA repair enzyme critical for microhomology mediated end joining (MMEJ). Polθ has limited expression in normal tissues but...
5.
Hatch S, Prevo R, Chan T, Millar V, Cornelissen B, Higgins G, et al.
STAR Protoc
. 2022 May;
3(2):101355.
PMID: 35542177
The colony formation assay is the gold-standard technique to assess cell viability after treatment with cytotoxic reagents, ionizing radiation, and cytotoxic combinatorial treatments. This protocol describes a high-throughput automated and...
6.
Nizami S, Millar V, Arunasalam K, Zarganes-Tzitzikas T, Brough D, Tresadern G, et al.
Sci Rep
. 2021 Oct;
11(1):20529.
PMID: 34635690
No abstract available.
7.
Nizami S, Millar V, Arunasalam K, Zarganes-Tzitzikas T, Brough D, Tresadern G, et al.
Sci Rep
. 2021 Jul;
11(1):15319.
PMID: 34321581
Inhibition of the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome has recently emerged as a promising therapeutic target for several inflammatory diseases. After priming and activation by inflammation...
8.
Zhang P, Kitchen-Smith I, Xiong L, Stracquadanio G, Brown K, Richter P, et al.
Cancer Res
. 2021 Feb;
81(7):1667-1680.
PMID: 33558336
Insights into oncogenesis derived from cancer susceptibility loci (SNP) hold the potential to facilitate better cancer management and treatment through precision oncology. However, therapeutic insights have thus far been limited...
9.
Gunn P, Pramfalk C, Millar V, Cornfield T, Hutchinson M, Johnson E, et al.
Physiol Rep
. 2020 Jul;
8(13):e14482.
PMID: 32643289
Background And Aims: Nonalcoholic fatty liver disease (NAFLD) begins with steatosis, where a mixed macrovesicular pattern of large and small lipid droplets (LDs) develops. Since in vitro models recapitulating this...
10.
Howarth A, Schroder M, Montenegro R, Drewry D, Sailem H, Millar V, et al.
SLAS Discov
. 2020 May;
25(7):801-811.
PMID: 32458721
High-content screening to monitor disease-modifying phenotypes upon small-molecule addition has become an essential component of many drug and target discovery platforms. One of the most common phenotypic approaches, especially in...