Un-Jung Yun
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Explore the profile of Un-Jung Yun including associated specialties, affiliations and a list of published articles.
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13
Citations
408
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0
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Recent Articles
1.
Kim C, Koh J, Shin S, Shin J, Hong M, Chung H, et al.
Cell Rep Med
. 2023 Oct;
4(11):101251.
PMID: 37890486
Evidence on whether prior antibiotic (pATB) administration modulates outcomes of programmed cell death protein-1 (PD-1) inhibitors in advanced gastric cancer (AGC) is scarce. In this study, we find that pATB...
2.
Kim C, Jung M, Kim H, Lee C, Jeung H, Koo D, et al.
J Clin Oncol
. 2023 Jun;
41(27):4394-4405.
PMID: 37364218
Purpose: Trastuzumab-containing chemotherapy is the recommended first-line regimen for human epidermal growth factor receptor 2 (HER2)-positive advanced gastric or gastroesophageal junction (G/GEJ) cancer. We evaluated the safety and efficacy of...
3.
Kim Y, Bak S, Lee W, Bae S, Lee E, Yang J, et al.
J Ginseng Res
. 2023 May;
47(3):479-491.
PMID: 37252280
Background: Hepatocellular carcinoma (HCC) has a high incidence and is one of the highest mortality cancers when advanced stage is proceeded. However, Anti-cancer drugs available for treatment are limited and...
4.
Yun U, Bae S, Song Y, Kim Y
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163776
Liver cancer has relatively few early symptoms and is usually diagnosed in the advanced stage. Sorafenib is the only first-line anticancer drug approved by the Food and Drug Administration (FDA)...
5.
Kim K, Yun U, Yeom S, Kim S, Lee H, Ahn S, et al.
Biomolecules
. 2021 Dec;
11(12).
PMID: 34944451
Chemotherapy is an essential strategy for cancer treatment. On the other hand, consistent exposure to chemotherapeutic drugs induces chemo-resistance in cancer cells through a variety of mechanisms. Therefore, it is...
6.
Han H, Sung J, Kim S, Yun U, Kim H, Jang E, et al.
Cancer Lett
. 2021 Mar;
508:59-72.
PMID: 33771684
The loss of cell-matrix interactions induces apoptosis, known as anoikis. For successful distant metastasis, circulating tumor cells (CTCs) that have lost matrix attachment need to acquire anoikis resistance in order...
7.
Yun U, Lee I, Lee J, Shim J, Kim Y
Cancers (Basel)
. 2020 Mar;
12(3).
PMID: 32151067
Novel strategies for overcoming multidrug resistance are urgently needed to improve chemotherapy success and reduce side effects. Ginsenosides, the main active components of , display anti-cancer properties and reverse drug...
8.
Yun U, Lee J, Shim J, Yoon K, Goh S, Yi E, et al.
Lab Invest
. 2019 Feb;
99(8):1157-1172.
PMID: 30700846
Doxorubicin is a widely used DNA damage-inducing anti-cancer drug. However, its use is limited by its dose-dependent side effects, such as cardiac toxicity. Cholesterol-lowering statin drugs increase the efficacy of...
9.
Yun U, Sung J, Park S, Ye S, Shim J, Lee J, et al.
Cell Death Dis
. 2017 Feb;
8(2):e2621.
PMID: 28230863
Rab escort protein-1 (REP1) is linked to choroideremia (CHM), an X-linked degenerative disorder caused by mutations of the gene encoding REP1 (CHM). REP1 mutant zebrafish showed excessive cell death throughout...
10.
Lee E, Yun U, Koo K, Sung J, Shim J, Ye S, et al.
Biochim Biophys Acta
. 2013 Oct;
1841(1):190-203.
PMID: 24120917
Lipid rafts, plasma membrane microdomains, are important for cell survival signaling and cholesterol is a critical lipid component for lipid raft integrity and function. DHA is known to have poor...