Jae-Seon Lee
Overview
Explore the profile of Jae-Seon Lee including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
2534
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Recent Articles
1.
Kang D, Sung J, Hwang H, Baek Y, Kim M, Lim G, et al.
Cancer Lett
. 2025 Feb;
615:217530.
PMID: 39961431
SF3B4, a splicing factor known to regulate mRNA expression and function, is upregulated in various cancers. Despite its potential significance, the mechanisms through which SF3B4 regulates nonsense-mediated mRNA decay (NMD)...
2.
Hwang H, Kang D, Shin J, Jung J, Ko S, Jung K, et al.
Nat Commun
. 2025 Jan;
16(1):353.
PMID: 39753537
Conventional chemotherapy- and radiotherapy-induced cancer senescence, which is characterized by poor proliferation, drug resistance, and senescence-associated secretory phenotype, has gained attention as contributing to cancer relapse and the development of...
3.
Kim H, Cho Y, Lee J, Oh E, Park H
Int J Biol Sci
. 2024 Oct;
20(13):5272-5292.
PMID: 39430246
Metastasis is a major cause of treatment failure in patients with pancreatic cancer, highlighting the urgent need for effective therapeutic strategies. Here, we focused on identifying novel miRNAs with key...
4.
Hwang H, Kang D, Kim J, Choi J, Ryu J, Herman A, et al.
JCI Insight
. 2024 Apr;
9(7).
PMID: 38587072
The roles of fibronectin leucine-rich transmembrane protein 2 (FLRT2) in physiological and pathological processes are not well known. Here, we identify a potentially novel function of FLRT2 in preventing endothelial...
5.
Kim H, Jung S, Yun H, Yoo K, Lee J, Lee J
Biochem Biophys Res Commun
. 2024 Jan;
695:149484.
PMID: 38211530
Ubiquitination factor E4B (UBE4B) has a tumor-promoting effect, demonstrated by its aberrant expression in various types of cancers, and in vitro studies have shown that the retardation of cancer cell...
6.
Kang D, Hwang H, Baek Y, Sung J, Kim K, Park H, et al.
Cell Death Dis
. 2024 Jan;
15(1):26.
PMID: 38199981
The ubiquitin-proteasome system is a vital protein degradation system that is involved in various cellular processes, such as cell cycle progression, apoptosis, and differentiation. Dysregulation of this system has been...
7.
Subedi S, Hwang H, Kang D, Mehta P, Kim N, Park H, et al.
Biosens Bioelectron
. 2023 Aug;
238:115595.
PMID: 37595478
Heparan sulfate (HS) plays a critical role in various biological processes as a vital component of the extracellular matrix. In this study, we synthesized three fluorescent probes (1-3) comprising Arg-rich...
8.
Jung S, Riew T, Yun H, Lim J, Hwang J, Jung S, et al.
Int J Mol Sci
. 2023 Jun;
24(11).
PMID: 37298584
Bcl-2-interacting cell death suppressor (BIS), also called BAG3, plays a role in physiological functions such as anti-apoptosis, cell proliferation, autophagy, and senescence. Whole-body -knockout (KO) mice exhibit early lethality accompanied...
9.
Melatonin and Exercise Counteract Sarcopenic Obesity through Preservation of Satellite Cell Function
Mankhong S, Kim S, Moon S, Lee J, Cho E, Kwak H, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047070
Sarcopenic obesity (SO) is characterized by atrophic skeletal muscle impairment (sarcopenia) and obesity, which is associated with adverse outcomes of morbidity and mortality in elderly people. We investigated the effects...
10.
Oh E, Kim H, Kim C, Lee J, Kim C, Lee J, et al.
Theranostics
. 2023 Feb;
13(3):873-895.
PMID: 36793872
Overexpression of NAD(P)H:quinone oxidoreductase 1 (NQO1) is associated with tumor cell proliferation and growth in several human cancer types. However, the molecular mechanisms underlying the activity of NQO1 in cell...