In Hye Lee
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Explore the profile of In Hye Lee including associated specialties, affiliations and a list of published articles.
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30
Citations
2570
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Recent Articles
1.
Hur Y, Lee H, Yoo J, Park Y, Lee I, Bae Y
Free Radic Biol Med
. 2024 Dec;
227():246-259.
PMID: 39645205
There is growing evidence that NADPH oxidase 4 (Nox4) in hepatocytes contributes to liver inflammation and fibrosis during the development of metabolic dysfunction-associated steatohepatitis (MASH). However, how Nox4 is regulated...
2.
Hur Y, Chae J, Choi M, Park K, Bae D, Park S, et al.
Biomol Ther (Seoul)
. 2024 Dec;
33(1):210-220.
PMID: 39632646
Previous studies have shown that testosterone activates the GPRC6A-Duox1 axis, resulting in the production of HO which leads to the apoptosis of keratinocytes and ultimately hair loss. Here, we elucidated...
3.
Hwang M, Park J, Ham Y, Lee I, Chun K
Int J Biol Sci
. 2023 Nov;
19(16):5245-5256.
PMID: 37928271
Adipocytes are adipose tissues that supply energy to the body through lipids. The two main types of adipocytes comprise white adipocytes (WAT) that store energy, and brown adipocytes (BAT), which...
4.
Hwang M, Baek J, Song J, Lee I, Chun K
BMB Rep
. 2023 Jan;
56(4):246-251.
PMID: 36646438
Obesity increases the risk of mortality and morbidity because it results in hypertension, heart disease, and type 2 diabetes. Therefore, there is an urgent need for pharmacotherapeutic drugs to treat...
5.
Jin Y, Ji Y, Song Y, Choe S, Jeon Y, Na H, et al.
Diabetes
. 2020 Oct;
70(1):182-195.
PMID: 33046512
/ is a core component of the class III phosphatidylinositol 3-kinase required for autophagosome formation and vesicular trafficking. Although has been implicated in numerous diseases such as cancer, aging, and...
6.
Yun U, Lee I, Lee J, Shim J, Kim Y
Cancers (Basel)
. 2020 Mar;
12(3).
PMID: 32151067
Novel strategies for overcoming multidrug resistance are urgently needed to improve chemotherapy success and reduce side effects. Ginsenosides, the main active components of , display anti-cancer properties and reverse drug...
7.
Song S, Park J, Chung G, Lee I, Hwang E
Metabolomics
. 2019 Oct;
15(10):137.
PMID: 31587111
Background: Nicotinamide (NAM) is a form of vitamin B3 that, when administered at near-gram doses, has been shown or suggested to be therapeutically effective against many diseases and conditions. The...
8.
Lee I
Exp Mol Med
. 2019 Sep;
51(9):1-11.
PMID: 31492861
Accumulating evidence has indicated that sirtuins are key components of diverse physiological processes, including metabolism and aging. Sirtuins confer protection from a wide array of metabolic and age-related diseases, such...
9.
Zhang W, Feng Y, Guo Q, Guo W, Xu H, Li X, et al.
Cell Death Differ
. 2019 Jun;
27(2):482-496.
PMID: 31209362
Both the stress-response protein, SIRT1, and the cell cycle checkpoint kinase, CHK2, play critical roles in aging and cancer via the modulation of cellular homeostasis and the maintenance of genomic...
10.
Lee I, Kim K, Kim Y, Kim Y, Shin D
J Nanosci Nanotechnol
. 2019 Mar;
19(8):4583-4589.
PMID: 30913752
Novel blue thermally activated delayed fluorescence (TADF) emitters, and , were designed and synthesized. Diphenyl sulfone (DPS) group functioned as a common acceptor, and it combined with each of two...