Ugo Perricone
Overview
Explore the profile of Ugo Perricone including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
216
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Recent Articles
1.
Gulotta M, Perricone U, Rubino P, Bonura A, Feo S, Giallongo A, et al.
ACS Omega
. 2025 Feb;
10(5):5036-5046.
PMID: 39959117
Alpha-enolase (ENO1) is a multifunctional protein with oncogenic roles. First described as a glycolytic enzyme, the protein performs different functions according to its cellular localization, post-translational modifications, and binding partners....
2.
Viesi E, Perricone U, Aloy P, Giugno R
J Cheminform
. 2025 Jan;
17(1):13.
PMID: 39891207
More sophisticated representations of compounds attempt to incorporate not only information on the structure and physicochemical properties of molecules, but also knowledge about their biological traits, leading to the so-called...
3.
DAnna L, Froux A, Rainot A, Spinello A, Perricone U, Barbault F, et al.
Chemistry
. 2024 Oct;
30(71):e202403572.
PMID: 39365977
The presence of a guanine quadruplex in the opening reading frame of the messenger RNA coding for the transmembrane serine protease 2 (TMPRSS2) may pave the way to original anticancer...
4.
Lombino J, Vallone R, Cimino M, Gulotta M, De Simone G, Morando M, et al.
Clin Epigenetics
. 2023 Dec;
15(1):197.
PMID: 38129913
Background: Lysine demethylase enzymes (KDMs) are an emerging class of therapeutic targets, that catalyse the removal of methyl marks from histone lysine residues regulating chromatin structure and gene expression. KDM4A...
5.
DAnna L, Miclot T, Bignon E, Perricone U, Barone G, Monari A, et al.
Chem Sci
. 2023 Oct;
14(41):11332-11339.
PMID: 37886086
The genome of SARS-CoV-2 coronavirus is made up of a single-stranded RNA fragment that can assume a specific secondary structure, whose stability can influence the virus's ability to reproduce. Recent...
6.
Schimunek J, Seidl P, Elez K, Hempel T, Le T, Noe F, et al.
Mol Inform
. 2023 Oct;
43(1):e202300262.
PMID: 37833243
The COVID-19 pandemic continues to pose a substantial threat to human lives and is likely to do so for years to come. Despite the availability of vaccines, searching for efficient...
7.
Viesi E, Sardina D, Perricone U, Giugno R
Database (Oxford)
. 2023 Jul;
2023.
PMID: 37450416
The World Health Organization estimates that 9 out of 10 people worldwide breathe air containing high levels of pollutants. Long-term and chronic exposure to high concentrations of air pollutants is...
8.
Culletta G, Tutone M, Ettari R, Perricone U, Di Chio C, Almerico A, et al.
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37445688
Immunoproteasome inhibition is a promising strategy for the treatment of hematological malignancies, autoimmune diseases, and inflammatory diseases. The design of non-covalent inhibitors of the immunoproteasome β1i/β5i catalytic subunits could be...
9.
De Simone G, Sardina D, Gulotta M, Perricone U
Sci Rep
. 2022 Oct;
12(1):17877.
PMID: 36284125
The family of protein kinases comprises more than 500 genes involved in numerous functions. Hence, their physiological dysfunction has paved the way toward drug discovery for cancer, cardiovascular, and inflammatory...
10.
Carreca A, Gaetani M, Busa R, Francipane M, Gulotta M, Perricone U, et al.
Viruses
. 2022 Jul;
14(7).
PMID: 35891518
Natural killer (NK) cells mount an immune response against hepatitis C virus (HCV) infection and can be activated by several cytokines, including interleukin-2 (IL-2), IL-15, and interferon-alpha (IFN-α). By exploiting...