Marco Tutone
Overview
Explore the profile of Marco Tutone including associated specialties, affiliations and a list of published articles.
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Articles
70
Citations
496
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Recent Articles
1.
Culletta G, Almerico A, Tutone M
Curr Med Chem
. 2025 Jan;
PMID: 39781710
CDK2 plays a pivotal role in controlling the cell cycle progression in eukaryotes and for this reason, it has been the subject of several studies for suitable inhibitors in the...
2.
Suryawanshi R, Shimpi R, Muralidharan V, Nemade L, Gurugubelli S, Baig S, et al.
Chem Biodivers
. 2024 Dec;
e202402738.
PMID: 39714369
Today the alarming situation of diabetes seeks innovative antidiabetic medications, especially those derived from natural sources, as natural substances are safer than manufactured pharmaceuticals. Therefore, this study investigated the inhibitory...
3.
Ippolito M, Benenati V, Gambino V, Lapi M, Nicosia D, Pace A, et al.
Clin Case Rep
. 2024 Dec;
12(12):e9671.
PMID: 39649500
We here describe a rare case of a 26-year-old male patient, presenting to our hospital after a motorcycle-car accident for the surgical management of long-bone fractures to the tibia and...
4.
Fiduccia I, Corrao F, Zizzo M, Perriera R, Genovese F, Vitale E, et al.
Mol Ther
. 2024 Oct;
32(12):4514-4523.
PMID: 39473179
Nonsense mutations, often resulting from single-nucleotide substitutions, produce mRNA harboring a premature termination codon (PTC), which causes the premature termination of protein synthesis. This produces truncated and non-functional proteins, which...
5.
Scalia F, Culletta G, Barreca M, Caruso Bavisotto C, Bivacqua R, DAmico G, et al.
Eur J Med Chem
. 2024 Sep;
278:116809.
PMID: 39226706
The correction of protein folding is fundamental for cellular functionality and its failure can lead to severe diseases. In this context, molecular chaperones are crucial players involved in the tricky...
6.
Filgueira de Azevedo Jr W, Quiroga R, Villarreal M, da Silveira N, Bitencourt-Ferreira G, da Silva A, et al.
J Comput Chem
. 2024 Jun;
45(27):2333-2346.
PMID: 38900052
Classical scoring functions may exhibit low accuracy in determining ligand binding affinity for proteins. The availability of both protein-ligand structures and affinity data make it possible to develop machine-learning models...
7.
Calcagno A, Tutone M, Del Re S, Delmonte S, Agosta D, Ghisetti V, et al.
Clin Infect Dis
. 2024 Apr;
80(2):476-477.
PMID: 38655679
No abstract available.
8.
Al Amin M, Dehbia Z, Nafady M, Zehravi M, Kumar K, Akiful Haque M, et al.
Mol Cell Biochem
. 2024 Apr;
480(1):43-73.
PMID: 38568359
Neurodegeneration, which manifests as several chronic and incurable diseases, is an age-related condition that affects the central nervous system (CNS) and poses a significant threat to the public's health for...
9.
Culletta G, Buttari B, Arese M, Brogi S, Almerico A, Saso L, et al.
Eur J Med Chem
. 2024 Mar;
270:116355.
PMID: 38555855
By controlling several antioxidant and detoxifying genes at the transcriptional level, including NAD(P)H quinone oxidoreductase 1 (NQO1), multidrug resistance-associated proteins (MRPs), UDP-glucuronosyltransferase (UGT), glutamate-cysteine ligase catalytic (GCLC) and modifier (GCLM)...
10.