Anna Maria Almerico
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Explore the profile of Anna Maria Almerico including associated specialties, affiliations and a list of published articles.
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76
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457
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Recent Articles
1.
Culletta G, Almerico A, Tutone M
Curr Med Chem
. 2025 Jan;
PMID: 39781710
CDK2 plays a pivotal role in controlling the cell cycle progression in eukaryotes and for this reason, it has been the subject of several studies for suitable inhibitors in the...
2.
Scalia F, Culletta G, Barreca M, Caruso Bavisotto C, Bivacqua R, DAmico G, et al.
Eur J Med Chem
. 2024 Sep;
278:116809.
PMID: 39226706
The correction of protein folding is fundamental for cellular functionality and its failure can lead to severe diseases. In this context, molecular chaperones are crucial players involved in the tricky...
3.
Culletta G, Buttari B, Arese M, Brogi S, Almerico A, Saso L, et al.
Eur J Med Chem
. 2024 Mar;
270:116355.
PMID: 38555855
By controlling several antioxidant and detoxifying genes at the transcriptional level, including NAD(P)H quinone oxidoreductase 1 (NQO1), multidrug resistance-associated proteins (MRPs), UDP-glucuronosyltransferase (UGT), glutamate-cysteine ligase catalytic (GCLC) and modifier (GCLM)...
4.
5.
Culletta G, Tutone M, Ettari R, Perricone U, Di Chio C, Almerico A, et al.
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37445688
Immunoproteasome inhibition is a promising strategy for the treatment of hematological malignancies, autoimmune diseases, and inflammatory diseases. The design of non-covalent inhibitors of the immunoproteasome β1i/β5i catalytic subunits could be...
6.
Mingoia F, Di Sano C, DAnna C, Fazzari M, Minafra L, Bono A, et al.
Eur J Med Chem
. 2023 Jun;
258:115537.
PMID: 37329715
A series of biologically unexplored substituted 1,3,4-subtituted-pyrrolo[3,2-c]quinoline derivatives (PQs) was evaluated against a panel of about 60 tumor cells (NCI). Based on the preliminary antiproliferative data, the optimizations efforts permitted...
7.
Carollo P, Tutone M, Culletta G, Fiduccia I, Corrao F, Pibiri I, et al.
Int J Mol Sci
. 2023 Jun;
24(11).
PMID: 37298560
Cystic Fibrosis (CF) is an autosomal recessive genetic disease caused by mutations in the CFTR gene, coding for the CFTR chloride channel. About 10% of the CFTR gene mutations are...
8.
Culletta G, Almerico A, Tutone M
Recent Adv Inflamm Allergy Drug Discov
. 2023 Mar;
17(2):88-95.
PMID: 36959140
No abstract available.
9.
Akiful Haque M, Marathakam A, Rana R, Almehmadi S, Tambe V, Charde M, et al.
Molecules
. 2023 Jan;
28(2).
PMID: 36677558
The present work describes the design and development of seventeen pyrimidine-clubbed benzimidazole derivatives as potential dihydrofolate reductase (DHFR) inhibitors. These compounds were filtered by using ADMET, drug-likeness characteristics calculations, and...
10.
Culletta G, Tutone M, Zappala M, Almerico A
Curr Med Chem
. 2022 Aug;
30(2):128-163.
PMID: 35909290
Background: The -SONH- group is of great significance in modern pharmaceutical use since, in sulfa-drugs, it is possible to introduce easily chemical modifications, and even small changes may lead to...