Trevor E Randall
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Explore the profile of Trevor E Randall including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
421
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Recent Articles
1.
Granton E, Brown L, Defaye M, Moazen P, Almblad H, Randall T, et al.
Cell
. 2024 Mar;
187(8):1874-1888.e14.
PMID: 38518773
Infections of the lung cause observable sickness thought to be secondary to inflammation. Signs of sickness are crucial to alert others via behavioral-immune responses to limit contact with contagious individuals....
2.
Randall T, Eckartt K, Kakumanu S, Price-Whelan A, Dietrich L, Harrison J
J Bacteriol
. 2021 Oct;
204(2):e0043321.
PMID: 34606374
Cyclic diguanylate (c-di-GMP) signal transduction systems provide bacteria with the ability to sense changing cell status or environmental conditions and then execute suitable physiological and social behaviors in response. In...
3.
Almblad H, Randall T, Liu F, LeBlanc K, Groves R, Kittichotirat W, et al.
Nat Commun
. 2021 Apr;
12(1):1986.
PMID: 33790266
Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, we identify a thermosensory diguanylate cyclase (TdcA) that modulates temperature-dependent motility, biofilm development...
4.
Marmont L, Whitfield G, Pfoh R, Williams R, Randall T, Ostaszewski A, et al.
J Biol Chem
. 2020 Jul;
295(34):11949-11962.
PMID: 32601062
Pel is a GalNAc-rich bacterial polysaccharide that contributes to the structure and function of biofilms. The operon is highly conserved among diverse bacterial species, and Pel may therefore be a...
5.
Harrison J, Almblad H, Irie Y, Wolter D, Eggleston H, Randall T, et al.
PLoS Genet
. 2020 Jun;
16(6):e1008848.
PMID: 32530919
Pseudomonas aeruginosa colonizes the airways of cystic fibrosis (CF) patients, causing infections that can last for decades. During the course of these infections, P. aeruginosa undergoes a number of genetic...
6.
Eli D, Randall T, Almblad H, Harrison J, Banin E
Methods Mol Biol
. 2017 Sep;
1657:263-278.
PMID: 28889300
The second messenger, cyclic diguanylate (c-di-GMP), regulates a variety of bacterial cellular and social behaviors. A key determinant of c-di-GMP levels in cells is its degradation by c-di-GMP-specific phosphodiesterases (PDEs)....
7.
Hmelo L, Borlee B, Almblad H, Love M, Randall T, Tseng B, et al.
Nat Protoc
. 2015 Oct;
10(11):1820-41.
PMID: 26492139
Allelic exchange is an efficient method of bacterial genome engineering. This protocol describes the use of this technique to make gene knockouts and knock-ins, as well as single-nucleotide insertions, deletions...
8.
Cohen D, Mechold U, Nevenzal H, Yarmiyhu Y, Randall T, Bay D, et al.
Proc Natl Acad Sci U S A
. 2015 Aug;
112(36):11359-64.
PMID: 26305928
The second messenger cyclic diguanylate (c-di-GMP) controls diverse cellular processes among bacteria. Diguanylate cyclases synthesize c-di-GMP, whereas it is degraded by c-di-GMP-specific phosphodiesterases (PDEs). Nearly 80% of these PDEs are...