Joe J Harrison
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Explore the profile of Joe J Harrison including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Behrendt L, Alcolombri U, Hunter J, Smriga S, Mincer T, Lowenstein D, et al.
Science
. 2024 Sep;
385(6714):eaab2661.
PMID: 39265021
Lipids comprise a significant fraction of sinking organic matter in the ocean and play a crucial role in the carbon cycle. Despite this, our understanding of the processes that control...
2.
Razvi E, DiFrancesco B, Wasney G, Morrison Z, Tam J, Auger A, et al.
Microbiol Spectr
. 2023 Apr;
11(3):e0029623.
PMID: 37098898
Biosynthesis of the Pel exopolysaccharide in Pseudomonas aeruginosa requires all seven genes of the operon. The periplasmic modification enzyme PelA contains a C-terminal deacetylase domain that is necessary for Pel-dependent...
3.
Razvi E, Whitfield G, Reichhardt C, Dreifus J, Willis A, Gluscencova O, et al.
NPJ Biofilms Microbiomes
. 2023 Feb;
9(1):7.
PMID: 36732330
Pel exopolysaccharide biosynthetic loci are phylogenetically widespread biofilm matrix determinants in bacteria. In Pseudomonas aeruginosa, Pel is crucial for cell-to-cell interactions and reducing susceptibility to antibiotic and mucolytic treatments. While...
4.
Acosta N, Bautista M, Waddell B, Du K, McCalder J, Pradhan P, et al.
J Med Virol
. 2022 Dec;
95(2):e28442.
PMID: 36579780
Wastewater-based SARS-CoV-2 surveillance enables unbiased and comprehensive monitoring of defined sewersheds. We performed real-time monitoring of hospital wastewater that differentiated Delta and Omicron variants within total SARS-CoV-2-RNA, enabling correlation to...
5.
Feehan D, Jamil K, Polyak M, Ogbomo H, Hasell M, Li S, et al.
PLoS Pathog
. 2022 Feb;
18(2):e1010325.
PMID: 35202434
Pseudomonas aeruginosa is an opportunistic pathogen that often infects individuals with the genetic disease cystic fibrosis, and contributes to airway blockage and loss of lung function. Natural killer (NK) cells...
6.
Randall T, Eckartt K, Kakumanu S, Price-Whelan A, Dietrich L, Harrison J
J Bacteriol
. 2021 Oct;
204(2):e0043321.
PMID: 34606374
Cyclic diguanylate (c-di-GMP) signal transduction systems provide bacteria with the ability to sense changing cell status or environmental conditions and then execute suitable physiological and social behaviors in response. In...
7.
Allkja J, Bjarnsholt T, Coenye T, Cos P, Fallarero A, Harrison J, et al.
Biofilm
. 2021 Jan;
2:100010.
PMID: 33447797
The lack of reproducibility of published studies is one of the major issues facing the scientific community, and the field of biofilm microbiology has been no exception. One effective strategy...
8.
Harrison J, Parsek M, Tseng B
Trends Microbiol
. 2020 Nov;
29(1):5-7.
PMID: 33187833
Intricate gene regulatory networks control the transition between the planktonic and biofilm lifestyles in bacteria. New evidence from Mhatre et al. uncovers how various adaptive mutations that arose in a...
9.
Marmont L, Whitfield G, Pfoh R, Williams R, Randall T, Ostaszewski A, et al.
J Biol Chem
. 2020 Jul;
295(34):11949-11962.
PMID: 32601062
Pel is a GalNAc-rich bacterial polysaccharide that contributes to the structure and function of biofilms. The operon is highly conserved among diverse bacterial species, and Pel may therefore be a...
10.
Harrison J, Almblad H, Irie Y, Wolter D, Eggleston H, Randall T, et al.
PLoS Genet
. 2020 Jun;
16(6):e1008848.
PMID: 32530919
Pseudomonas aeruginosa colonizes the airways of cystic fibrosis (CF) patients, causing infections that can last for decades. During the course of these infections, P. aeruginosa undergoes a number of genetic...