Toshiko Tanaka-Kagawa
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Explore the profile of Toshiko Tanaka-Kagawa including associated specialties, affiliations and a list of published articles.
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61
Citations
383
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Recent Articles
1.
Kanai T, Shirahata T, Nakamori S, Sato R, Hayashi A, Koizumi Y, et al.
Chem Pharm Bull (Tokyo)
. 2025 Mar;
73(3):195-204.
PMID: 40058828
This study established a H-NMR-based biochemometric approach for the isolation of biologically active compounds from complex extracts. In both pharmacognosy and natural product chemistry, reliably isolating bioactive compounds typically necessitates...
2.
Hanioka N, Isobe T, Saito K, Nagaoka K, Mori Y, Jinno H, et al.
Comp Biochem Physiol C Toxicol Pharmacol
. 2024 Jun;
283:109962.
PMID: 38889874
Tizoxanide (TZX) is an active metabolite of nitazoxanide (NTZ) originally developed as an antiparasitic agent, and is predominantly metabolized into TZX glucuronide. In the present study, TZX glucuronidation by the...
3.
Hanioka N, Isobe T, Saito K, Nagaoka K, Mori Y, Jinno H, et al.
Arch Toxicol
. 2024 Jan;
98(3):837-848.
PMID: 38182911
Tetrabromobisphenol A (TBBPA) and tetrachlorobisphenol A (TCBPA), bisphenol A (BPA) analogs, are endocrine-disrupting chemicals predominantly metabolized into glucuronides by UDP-glucuronosyltransferase (UGT) enzymes in humans and rats. In the present study,...
4.
Isobe T, Ohkawara S, Mori Y, Jinno H, Tanaka-Kagawa T, Hanioka N
Chem Biol Interact
. 2023 Jan;
372:110353.
PMID: 36657734
Phthalates are widely used plasticizers that are primarily and rapidly metabolized to monoester phthalates in mammals. In the present study, the hydrolysis of dibutyl phthalate (DBP) and di(2-ethylhexyl) phthalate (DEHP)...
5.
Mori Y, Tanaka-Kagawa T, Tahara M, Kawakami T, Aoki A, Okamoto Y, et al.
J Toxicol Sci
. 2023 Jan;
48(1):37-45.
PMID: 36599426
Transient Receptor Potential Ankyrin 1 (TRPA1), which is expressed in the airways, has causative and exacerbating roles in respiratory diseases. TRPA1 is known as a target of sick building syndrome-related...
6.
Mori Y, Aoki A, Okamoto Y, Isobe T, Ohkawara S, Hanioka N, et al.
Biol Pharm Bull
. 2022 Oct;
45(12):1839-1846.
PMID: 36223942
Phthalic acid (PA) diesters are widely used in consumer products, as plasticizers, and are ubiquitous environmental pollutants. There is a growing concern about their adjuvant effect on allergic diseases. Although...
7.
Mori Y, Aoki A, Okamoto Y, Isobe T, Ohkawara S, Hanioka N, et al.
Biol Pharm Bull
. 2022 Jul;
45(8):1185-1190.
PMID: 35908900
Bitter taste receptors (TAS2Rs) are expressed by oral cavity cells in mammals and classically function as sensors for bitter compounds. There are 25 functional isoforms of human TAS2Rs, with individual...
8.
Hanioka N, Tanaka-Kagawa T, Mori Y, Ikushiro S, Jinno H, Ohkawara S, et al.
Biol Pharm Bull
. 2022 Jul;
45(8):1116-1123.
PMID: 35908893
Flavones, which are distributed in a variety of plants and foods in nature, possess significant biological activities, including antitumor and anti-inflammatory effects, and are metabolized into glucuronides by uridine 5'-diphosphate...
9.
Sugita T, Tanaka-Kagawa T
Yakugaku Zasshi
. 2022 Jan;
142(1):9-10.
PMID: 34980752
No abstract available.
10.
Hanioka N, Saito K, Isobe T, Ohkawara S, Jinno H, Tanaka-Kagawa T
Biopharm Drug Dispos
. 2021 Mar;
42(5):218-225.
PMID: 33754379
Favipiravir is an antiviral agent effective against several RNA viruses that is converted into an inactive oxidative metabolite (M1), mainly by aldehyde oxidase, in humans. In the present study, the...