The Journal of Toxicological Sciences
Overview
The Journal of Toxicological Sciences is a peer-reviewed scientific journal that publishes original research articles, reviews, and case reports in the field of toxicology. It covers a wide range of topics including toxic substances, their effects on living organisms, mechanisms of toxicity, risk assessment, and toxicological testing methods. The journal aims to provide a platform for researchers and professionals to share their findings and contribute to the advancement of toxicological sciences.
Details
Details
Abbr.
J Toxicol Sci
Start
1976
End
Continuing
Frequency
Quarterly
p-ISSN
0388-1350
e-ISSN
1880-3989
Country
Japan
Languages
English
Japanese
Japanese
Specialty
Toxicology
Metrics
Metrics
h-index / Ranks: 6235
59
SJR / Ranks: 9309
473
CiteScore / Ranks: 7225
3.70
JIF / Ranks: 5186
2.0
Recent Articles
1.
Fujii Y, Harada K
J Toxicol Sci
. 2025 Mar;
50(3):97-104.
PMID: 40024759
Per- and polyfluoroalkyl substances (PFAS) are a group of chemicals containing stable per- or polyfluoroalkyl groups. Recent epidemiological studies have shown that PFAS cause health risks even at low concentrations....
2.
Ishihara N, Tanaka M, Namba K, Kawano S, Nishimura S, Nezu N, et al.
J Toxicol Sci
. 2025 Mar;
50(3):147-159.
PMID: 40024758
Exposure to fine particulate matter (PM) has been epidemiologically reported to worsen the prognosis of ischemic stroke; however, the details have not been investigated. One of the major toxic mechanisms...
3.
Uzu M, Takezawa T
J Toxicol Sci
. 2025 Mar;
50(3):135-145.
PMID: 40024757
Cholestatic drug-induced liver injury (DILI) is caused by the aberrant excretion of bile acids (BAs) from hepatocytes via bile canaliculus-like structures (BCLSs) into the bile ducts. The precise in vitro...
4.
Fujimoto K, Kishino H, Hirao J, Maejima T, Mori K, Tsuchiya Y
J Toxicol Sci
. 2025 Mar;
50(3):125-134.
PMID: 40024756
In a 3-month repeated oral dose toxicity study of DS-1971a, a selective inhibitor of the Nav1.7 voltage-gated sodium channel, fatty change of hepatocytes was observed only in male rats at...
5.
Katsuki H, Yamada T, Ayukawa K
J Toxicol Sci
. 2025 Mar;
50(3):117-123.
PMID: 40024755
Prolongation of QRS duration (prolonged QRS) is associated with severe outcomes in non-tricyclic antidepressant poisoning. However, factors other than xenobiotics affecting QRS duration have not yet been investigated. Hence, this...
6.
Tamura A, Kitayama K, Adachi M, Hashimoto K, Oguro A, Imaoka S
J Toxicol Sci
. 2025 Mar;
50(3):105-116.
PMID: 40024754
Hypoxia induces the expression of nuclear factor kappa B (NF-kappa-B). NF-kappa-B functions by forming dimers from five main subunits: p65 (RelA), RelB, p52, p50, and c-Rel. In the classical pathway,...
7.
Shimada M, Hosokawa Y, Ihara R, Ogata K, Iwashita K, Matsuyama R, et al.
J Toxicol Sci
. 2025 Feb;
50(2):83-95.
PMID: 39894538
Attainment of vaginal patency is an endpoint for the onset of puberty in female animals in toxicity studies. It is widely acknowledged that certain substances with endocrine-modulating effects can influence...
8.
Sato H, Umehara T, Kimura S, Tanaka T, Kim S
J Toxicol Sci
. 2025 Feb;
50(2):75-81.
PMID: 39894537
The surface of a rotting corpse is covered with liquid decomposition products that have flowed out of the body that include putrefactive amines produced via putrefaction and decarboxylation reactions of...
9.
Kaneko T, Fujita M, Tsuruta R
J Toxicol Sci
. 2025 Feb;
50(2):69-73.
PMID: 39894536
Acute carbon monoxide poisoning (ACOP) is a cause of accidental or deliberate deaths worldwide. Subsequent complications, particularly delayed neurological sequelae (DNS), are preventable and treatable based on their pathophysiology. Hyperbaric...
10.
Yamamoto S, Yoshida K, Matsumoto M, Yamada T
J Toxicol Sci
. 2025 Feb;
50(2):57-68.
PMID: 39894535
A physiologically based kinetic (PBK) model is used for predicting chemical concentrations of toxicological concern in target tissues. Such models are important for understanding toxicokinetics. However, it is challenging to...