Toni M Delorey
Overview
Explore the profile of Toni M Delorey including associated specialties, affiliations and a list of published articles.
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11
Citations
1603
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Recent Articles
1.
Pita-Juarez Y, Karagkouni D, Kalavros N, Melms J, Niezen S, Delorey T, et al.
Genome Biol
. 2025 Mar;
26(1):56.
PMID: 40087773
Background: The molecular underpinnings of organ dysfunction in severe COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function,...
2.
Ding J, Garber J, Uchida A, Lefkovith A, Carter G, Vimalathas P, et al.
Nat Commun
. 2024 Apr;
15(1):3344.
PMID: 38637492
Coordinated cell interactions within the esophagus maintain homeostasis, and disruption can lead to eosinophilic esophagitis (EoE), a chronic inflammatory disease with poorly understood pathogenesis. We profile 421,312 individual cells from...
3.
Fiskin E, Eraslan G, Alora-Palli M, Leyva-Castillo J, Kim S, Choe H, et al.
bioRxiv
. 2023 Nov;
PMID: 37961084
In healthy skin, a cutaneous immune system maintains the balance between tolerance towards innocuous environmental antigens and immune responses against pathological agents. In atopic dermatitis (AD), barrier and immune dysfunction...
4.
Scheid J, Eraslan B, Hudak A, Brown E, Sergio D, Delorey T, et al.
J Exp Med
. 2023 Feb;
220(4).
PMID: 36752797
Plasma cells (PCs) constitute a significant fraction of colonic mucosal cells and contribute to inflammatory infiltrates in ulcerative colitis (UC). While gut PCs secrete bacteria-targeting IgA antibodies, their role in...
5.
Pita-Juarez Y, Karagkouni D, Kalavros N, Melms J, Niezen S, Delorey T, et al.
bioRxiv
. 2022 Nov;
PMID: 36324805
The molecular underpinnings of organ dysfunction in acute COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function, we...
6.
Pedersen T, Brown E, Plichta D, Johansen J, Twardus S, Delorey T, et al.
Immunity
. 2022 Sep;
55(10):1909-1923.e6.
PMID: 36115338
Reciprocal interactions between host T helper cells and gut microbiota enforce local immunological tolerance and modulate extra-intestinal immunity. However, our understanding of antigen-specific tolerance to the microbiome is limited. Here,...
7.
Hodis E, Torlai Triglia E, Kwon J, Biancalani T, Zakka L, Parkar S, et al.
Science
. 2022 Apr;
376(6592):eabi8175.
PMID: 35482859
Establishing causal relationships between genetic alterations of human cancers and specific phenotypes of malignancy remains a challenge. We sequentially introduced mutations into healthy human melanocytes in up to five genes...
8.
Schnell A, Huang L, Singer M, Singaraju A, Barilla R, Regan B, et al.
Cell
. 2021 Dec;
184(26):6281-6298.e23.
PMID: 34875227
While intestinal Th17 cells are critical for maintaining tissue homeostasis, recent studies have implicated their roles in the development of extra-intestinal autoimmune diseases including multiple sclerosis. However, the mechanisms by...
9.
Delorey T, Ziegler C, Heimberg G, Normand R, Yang Y, Segerstolpe A, et al.
Nature
. 2021 Apr;
595(7865):107-113.
PMID: 33915569
COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress syndrome and multiple organ failure, but little is known about its pathophysiology. Here we generated single-cell atlases of...
10.
Delorey T, Ziegler C, Heimberg G, Normand R, Yang Y, Segerstolpe A, et al.
bioRxiv
. 2021 Mar;
PMID: 33655247
The SARS-CoV-2 pandemic has caused over 1 million deaths globally, mostly due to acute lung injury and acute respiratory distress syndrome, or direct complications resulting in multiple-organ failures. Little is...