Caroline B M Porter
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Explore the profile of Caroline B M Porter including associated specialties, affiliations and a list of published articles.
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22
Citations
2480
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Recent Articles
1.
Pita-Juarez Y, Karagkouni D, Kalavros N, Melms J, Niezen S, Delorey T, et al.
Genome Biol
. 2025 Mar;
26(1):56.
PMID: 40087773
Background: The molecular underpinnings of organ dysfunction in severe COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function,...
2.
Klughammer J, Abravanel D, Segerstolpe A, Blosser T, Goltsev Y, Cui Y, et al.
Nat Med
. 2024 Oct;
30(11):3236-3249.
PMID: 39478111
Although metastatic disease is the leading cause of cancer-related deaths, its tumor microenvironment remains poorly characterized due to technical and biospecimen limitations. In this study, we assembled a multi-modal spatial...
3.
Patel A, Ashenberg O, Collins N, Segerstolpe A, Jiang S, Slyper M, et al.
bioRxiv
. 2024 Jan;
PMID: 38260392
Neuroblastoma is a pediatric cancer arising from the developing sympathoadrenal lineage with complex inter- and intra-tumoral heterogeneity. To chart this complexity, we generated a comprehensive cell atlas of 55 neuroblastoma...
4.
Pita-Juarez Y, Karagkouni D, Kalavros N, Melms J, Niezen S, Delorey T, et al.
bioRxiv
. 2022 Nov;
PMID: 36324805
The molecular underpinnings of organ dysfunction in acute COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function, we...
5.
Kaur G, Porter C, Ashenberg O, Lee J, Riesenfeld S, Hofree M, et al.
Nat Commun
. 2022 Jul;
13(1):4398.
PMID: 35906236
Fetal growth restriction (FGR) affects 5-10% of pregnancies, and can have serious consequences for both mother and child. Prevention and treatment are limited because FGR pathogenesis is poorly understood. Genetic...
6.
Hwang W, Jagadeesh K, Guo J, Hoffman H, Yadollahpour P, Reeves J, et al.
Nat Genet
. 2022 Jul;
54(8):1178-1191.
PMID: 35902743
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal and treatment-refractory cancer. Molecular stratification in pancreatic cancer remains rudimentary and does not yet inform clinical management or therapeutic development. Here, we...
7.
Luoma A, Suo S, Wang Y, Gunasti L, Porter C, Nabilsi N, et al.
Cell
. 2022 Jul;
185(16):2918-2935.e29.
PMID: 35803260
Neoadjuvant immune checkpoint blockade has shown promising clinical activity. Here, we characterized early kinetics in tumor-infiltrating and circulating immune cells in oral cancer patients treated with neoadjuvant anti-PD-1 or anti-PD-1/CTLA-4...
8.
Lobritz M, Andrews I, Braff D, Porter C, Gutierrez A, Furuta Y, et al.
Cell Chem Biol
. 2022 Jan;
29(2):276-286.e4.
PMID: 34990601
β-Lactam antibiotics disrupt the assembly of peptidoglycan (PG) within the bacterial cell wall by inhibiting the enzymatic activity of penicillin-binding proteins (PBPs). It was recently shown that β-lactam treatment initializes...
9.
Delorey T, Ziegler C, Heimberg G, Normand R, Yang Y, Segerstolpe A, et al.
Nature
. 2021 Apr;
595(7865):107-113.
PMID: 33915569
COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress syndrome and multiple organ failure, but little is known about its pathophysiology. Here we generated single-cell atlases of...
10.
Delorey T, Ziegler C, Heimberg G, Normand R, Yang Y, Segerstolpe A, et al.
bioRxiv
. 2021 Mar;
PMID: 33655247
The SARS-CoV-2 pandemic has caused over 1 million deaths globally, mostly due to acute lung injury and acute respiratory distress syndrome, or direct complications resulting in multiple-organ failures. Little is...