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Michal Slyper

Explore the profile of Michal Slyper including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 3914
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Recent Articles
1.
Pita-Juarez Y, Karagkouni D, Kalavros N, Melms J, Niezen S, Delorey T, et al.
Genome Biol . 2025 Mar; 26(1):56. PMID: 40087773
Background: The molecular underpinnings of organ dysfunction in severe COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function,...
2.
Klughammer J, Abravanel D, Segerstolpe A, Blosser T, Goltsev Y, Cui Y, et al.
Nat Med . 2024 Oct; 30(11):3236-3249. PMID: 39478111
Although metastatic disease is the leading cause of cancer-related deaths, its tumor microenvironment remains poorly characterized due to technical and biospecimen limitations. In this study, we assembled a multi-modal spatial...
3.
Subramanian A, Vernon K, Zhou Y, Marshall J, Alimova M, Arevalo C, et al.
Cell Rep . 2024 May; 43(6):114253. PMID: 38781074
Diabetic kidney disease (DKD), the most common cause of kidney failure, is a frequent complication of diabetes and obesity, and yet to date, treatments to halt its progression are lacking....
4.
Patel A, Ashenberg O, Collins N, Segerstolpe A, Jiang S, Slyper M, et al.
bioRxiv . 2024 Jan; PMID: 38260392
Neuroblastoma is a pediatric cancer arising from the developing sympathoadrenal lineage with complex inter- and intra-tumoral heterogeneity. To chart this complexity, we generated a comprehensive cell atlas of 55 neuroblastoma...
5.
Waghray A, Monga I, Lin B, Shah V, Slyper M, Giotti B, et al.
bioRxiv . 2023 Dec; PMID: 38076853
The human airway contains specialized rare epithelial cells whose roles in respiratory disease are not well understood. Ionocytes express the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), while chemosensory tuft cells...
6.
Fiskin E, Eraslan G, Alora-Palli M, Leyva-Castillo J, Kim S, Choe H, et al.
bioRxiv . 2023 Nov; PMID: 37961084
In healthy skin, a cutaneous immune system maintains the balance between tolerance towards innocuous environmental antigens and immune responses against pathological agents. In atopic dermatitis (AD), barrier and immune dysfunction...
7.
Zhao W, Kepecs B, Mahadevan N, Segerstolpe A, Weirather J, Besson N, et al.
bioRxiv . 2023 Jul; PMID: 37425718
is the most frequently mutated gene across many cancers and is associated with shorter survival in lung adenocarcinoma (LUAD). To define how mutations affect the LUAD tumor microenvironment (TME), we...
8.
Comiter C, Vaishnav E, Ciampricotti M, Li B, Yang Y, Rodig S, et al.
bioRxiv . 2023 Mar; PMID: 36993643
Tissue biology involves an intricate balance between cell-intrinsic processes and interactions between cells organized in specific spatial patterns, which can be respectively captured by single-cell profiling methods, such as single-cell...
9.
Suzzi S, Croese T, Ravid A, Gold O, Clark A, Medina S, et al.
Nat Commun . 2023 Mar; 14(1):1293. PMID: 36894557
Systemic immunity supports lifelong brain function. Obesity posits a chronic burden on systemic immunity. Independently, obesity was shown as a risk factor for Alzheimer's disease (AD). Here we show that...
10.
Pita-Juarez Y, Karagkouni D, Kalavros N, Melms J, Niezen S, Delorey T, et al.
bioRxiv . 2022 Nov; PMID: 36324805
The molecular underpinnings of organ dysfunction in acute COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function, we...