Tom Deroo
Overview
Explore the profile of Tom Deroo including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
504
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Recent Articles
1.
Gul I, Staal J, Hulpiau P, De Keuckelaere E, Kamm K, Deroo T, et al.
Genome Biol Evol
. 2018 Apr;
10(3):909-917.
PMID: 29608715
With the genomes available for many animal clades, including the early-branching metazoans, one can readily study the functional conservation of genes across a diversity of animal lineages. Ectopic expression of...
2.
Neupane J, Ghimire S, Vandewoestyne M, Lu Y, Gerris J, Van Coster R, et al.
Cell Rep
. 2015 Nov;
13(7):1304-1309.
PMID: 26549459
Variation in the level of mtDNA heteroplasmy in adult tissues is commonly seen in patients with a mixture of wild-type and mutant mtDNA. A mixture of different mtDNA variants may...
3.
Duggal G, Warrier S, Ghimire S, Broekaert D, van der Jeught M, Lierman S, et al.
Stem Cells
. 2015 Jun;
33(9):2686-98.
PMID: 26108678
Human embryonic stem cells (hESCs) closely resemble mouse epiblast stem cells exhibiting primed pluripotency unlike mouse ESCs (mESCs), which acquire a naïve pluripotent state. Efforts have been made to trigger...
4.
van der Jeught M, Taelman J, Duggal G, Ghimire S, Lierman S, Chuva de Sousa Lopes S, et al.
Cell Reprogram
. 2015 Jun;
17(3):170-80.
PMID: 26053517
In mice, inhibition of both the fibroblast growth factor (FGF) mitogen-activated protein kinase kinase/extracellular-signal regulated kinase (MEK/Erk) and the Wnt signaling inhibitor glycogen synthase-3β (GSK3β) enables the derivation of mouse...
5.
Ghimire S, Heindryckx B, van der Jeught M, Neupane J, OLeary T, Lierman S, et al.
Stem Cells Dev
. 2014 Sep;
24(4):497-506.
PMID: 25245024
Early lineage segregation in preimplantation embryos and maintenance of pluripotency in embryonic stem cells (ESCs) are both regulated by specific signaling pathways. Small molecules have been shown to modulate these...
6.
Neupane J, Vandewoestyne M, Ghimire S, Lu Y, Qian C, Van Coster R, et al.
Mitochondrion
. 2014 Sep;
18:27-33.
PMID: 25229667
To evaluate and compare mitochondrial DNA (mtDNA) carry-over and embryonic development potential between different nuclear transfer techniques we performed germinal vesicle nuclear transfer (GV NT), metaphase-II spindle-chromosome-complex (MII-SCC) transfer and...
7.
Nikiforaki D, Vanden Meerschaut F, De Gheselle S, Qian C, Van den Abbeel E, De Vos W, et al.
Fertil Steril
. 2014 Jun;
102(2):581-588.e1.
PMID: 24931205
Objective: To assess the Ca2+-releasing ability of sperm involved in partial hydatidiform moles. Design: Analysis of the activating and Ca2+-releasing ability of human sperm. Setting: University hospital research laboratory. Patient(s):...
8.
Duggal G, Heindryckx B, Deroo T, De Sutter P
Vet Q
. 2014 Mar;
34(1):42-51.
PMID: 24593843
In recent years, pluripotent stem cells have demonstrated to be exciting tools to understand embryonic development, cell lineage specification, tissue generation and repair, and various other biological processes. In addition,...
9.
Neupane J, Vandewoestyne M, Heindryckx B, Ghimire S, Lu Y, Qian C, et al.
Hum Reprod
. 2014 Feb;
29(4):852-9.
PMID: 24524987
Study Question: What is the reliability of preimplantation genetic diagnosis (PGD) based on polar body (PB), blastomere or trophectoderm (TE) analysis in a heteroplasmic mitochondrial mouse model? Summary Answer: The...
10.
van der Jeught M, Heindryckx B, OLeary T, Duggal G, Ghimire S, Lierman S, et al.
Hum Reprod
. 2013 Nov;
29(1):41-8.
PMID: 24256991
Study Question: Is there an effect of the TGFβ inhibitor SB431542 (SB) on the epiblast compartment of human blastocysts, and does it affect subsequent human embryonic stem cell (hESC) derivation?...