Bjorn Heindryckx
Overview
Explore the profile of Bjorn Heindryckx including associated specialties, affiliations and a list of published articles.
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87
Citations
1249
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Recent Articles
1.
Castelluccio N, Spath K, Li D, De Coo I, Butterworth L, Wells D, et al.
Hum Reprod Update
. 2025 Mar;
PMID: 40085924
Mitochondrial DNA (mtDNA) diseases pose unique challenges for genetic counselling and require tailored approaches to address recurrence risks and reproductive options. The intricate dynamics of mtDNA segregation and heteroplasmy shift...
2.
Cardona Barberan A, Reddy Guggilla R, Colenbier C, Van der Velden E, Rybouchkin A, Stoop D, et al.
Hum Reprod Open
. 2024 Oct;
2024(4):hoae057.
PMID: 39411542
Study Question: What is the frequency of , , and variants in male patients showing fertilization failure after ICSI, and how effective is assisted oocyte activation (AOA) for them? Summary...
3.
Pennings G, Heindryckx B, Stoop D, Mertes H
Reprod Biomed Online
. 2024 Jun;
49(3):104101.
PMID: 38943811
Research Question: What is the attitude of Belgian women of reproductive age towards enucleated egg donation? Does the willingness of women to donate differ when they would donate enucleated or...
4.
Christodoulaki A, He H, Zhou M, De Roo C, Baetens M, De Pretre T, et al.
Hum Reprod Open
. 2024 Mar;
2024(1):hoae009.
PMID: 38425578
Study Question: Is pronuclear transfer (PNT) capable of restoring embryo developmental arrest caused by cytoplasmic inferiority of -grown (IVG) mouse oocytes? Summary Answer: PNT to matured cytoplasm significantly improved embryo...
5.
Bekaert B, Boel A, De Witte L, Vandenberghe W, Popovic M, Stamatiadis P, et al.
Mol Ther
. 2023 Jun;
31(8):2326-2341.
PMID: 37376733
Human germline gene correction by targeted nucleases holds great promise for reducing mutation transmission. However, recent studies have reported concerning observations in CRISPR-Cas9-targeted human embryos, including mosaicism and loss of...
6.
Raes A, Wydooghe E, Pavani K, Pascottini O, Van Steendam K, Dhaenens M, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047535
While human in vitro embryo production is generally performed individually, animal models have shown that culturing embryos in groups improves blastocyst yield and quality. Paracrine embryotrophins could be responsible for...
7.
Athanasouli P, Balli M, De Jaime-Soguero A, Boel A, Papanikolaou S, van der Veer B, et al.
Nat Commun
. 2023 Mar;
14(1):1210.
PMID: 36869101
Early during preimplantation development and in heterogeneous mouse embryonic stem cells (mESC) culture, pluripotent cells are specified towards either the primed epiblast or the primitive endoderm (PE) lineage. Canonical Wnt...
8.
Pavani K, Meese T, Pascottini O, Guan X, Lin X, Peelman L, et al.
Proc Natl Acad Sci U S A
. 2022 Mar;
119(12):e2122708119.
PMID: 35298333
SignificanceHatching from the zona pellucida is a prerequisite for embryo implantation and is less likely to occur in vitro for reasons unknown. Extracellular vesicles (EVs) are secreted by the embryo...
9.
Tang M, Boel A, Castelluccio N, Cardona Barberan A, Christodoulaki A, Bekaert B, et al.
J Assist Reprod Genet
. 2022 Jan;
39(3):609-618.
PMID: 35064435
Purpose: Providing additional insights on the efficacy of human nuclear transfer (NT). Here, and earlier, NT has been applied to minimize transmission risk of mitochondrial DNA (mtDNA) diseases. NT has...
10.
Sex-Specific Isolation and Propagation of Human Premeiotic Fetal Germ Cells and Germ Cell-Like Cells
Mishra S, Taelman J, Chang Y, Boel A, De Sutter P, Heindryckx B, et al.
Cells
. 2021 Jun;
10(5).
PMID: 34065661
The second trimester of human development is marked by asynchronous gonadal development hampering the isolation of homogenous populations of early and late fetal germ cells (FGCs). We evaluated the feasibility...