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Jitesh Neupane

Explore the profile of Jitesh Neupane including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 80
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Recent Articles
1.
Wu B, Neupane J, Zhou Y, Zhang J, Chen Y, Surani M, et al.
Sci China Life Sci . 2025 Feb; PMID: 39969747
How a mammalian fertilized egg acquires totipotency and develops into a full-term offspring is a fundamental scientific question. Human embryonic development is difficult to study due to limited resources, technical...
2.
Neupane J, Wong F, Surani M
Cell Res . 2020 Jan; 30(2):103-104. PMID: 31913357
No abstract available.
3.
Ghimire S, van der Jeught M, Neupane J, Roost M, Anckaert J, Popovic M, et al.
Sci Rep . 2018 Apr; 8(1):5884. PMID: 29650979
Mouse embryonic stem cells (mESCs) exist in a naive, primed and ground state of pluripotency. While comparative analyses of these pluripotency states have been reported, the mESCs utilized originated from...
4.
Lu Y, Ferrer-Buitrago M, Popovic M, Neupane J, De Vos W, Lierman S, et al.
Reprod Biomed Online . 2018 Apr; 36(4):396-407. PMID: 29609767
Patients presenting with abnormally high numbers of immature oocytes at retrieval are more likely to exhibit maturation resistant oocytes. However, the clinical relevance of such events remains unknown. We investigated...
5.
Lu Y, Bonte D, Ferrer-Buitrago M, Popovic M, Neupane J, van der Jeught M, et al.
Reprod Fertil Dev . 2018 Jan; 30(7):991-1001. PMID: 29325603
Inconsistent fertilisation and pregnancy rates have been reported by different laboratories after application of ionomycin as a clinical method of assisted oocyte activation (AOA) to overcome fertilisation failure. Using both...
6.
Neupane J, Ghimire S, Vandewoestyne M, Lu Y, Gerris J, Van Coster R, et al.
Cell Rep . 2015 Nov; 13(7):1304-1309. PMID: 26549459
Variation in the level of mtDNA heteroplasmy in adult tissues is commonly seen in patients with a mixture of wild-type and mutant mtDNA. A mixture of different mtDNA variants may...
7.
Ghimire S, Heindryckx B, van der Jeught M, Neupane J, OLeary T, Lierman S, et al.
Stem Cells Dev . 2014 Sep; 24(4):497-506. PMID: 25245024
Early lineage segregation in preimplantation embryos and maintenance of pluripotency in embryonic stem cells (ESCs) are both regulated by specific signaling pathways. Small molecules have been shown to modulate these...
8.
Neupane J, Vandewoestyne M, Ghimire S, Lu Y, Qian C, Van Coster R, et al.
Mitochondrion . 2014 Sep; 18:27-33. PMID: 25229667
To evaluate and compare mitochondrial DNA (mtDNA) carry-over and embryonic development potential between different nuclear transfer techniques we performed germinal vesicle nuclear transfer (GV NT), metaphase-II spindle-chromosome-complex (MII-SCC) transfer and...
9.
Heindryckx B, Neupane J, Vandewoestyne M, Christodoulou C, Jackers Y, Gerris J, et al.
Mitochondrion . 2014 Aug; 18:12-7. PMID: 25159128
To investigate the applicability of preimplantation genetic diagnosis (PGD), we used trophectoderm (TE) biopsy to determine the mutation load in a 35-year-old female with mitochondrial encephalopathy, lactic acidosis and stroke-like...
10.
Neupane J, Vandewoestyne M, Heindryckx B, Ghimire S, Lu Y, Qian C, et al.
Hum Reprod . 2014 Feb; 29(4):852-9. PMID: 24524987
Study Question: What is the reliability of preimplantation genetic diagnosis (PGD) based on polar body (PB), blastomere or trophectoderm (TE) analysis in a heteroplasmic mitochondrial mouse model? Summary Answer: The...