Ting-Lin B Yang
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Explore the profile of Ting-Lin B Yang including associated specialties, affiliations and a list of published articles.
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10
Citations
450
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Recent Articles
1.
Wang F, Trier A, Li F, Kim S, Chen Z, Chai J, et al.
Cell
. 2021 Jan;
184(2):422-440.e17.
PMID: 33450207
Itch is an evolutionarily conserved sensation that facilitates expulsion of pathogens and noxious stimuli from the skin. However, in organ failure, cancer, and chronic inflammatory disorders such as atopic dermatitis...
2.
Yang T, Kim B
Immunity
. 2020 Aug;
53(2):235-237.
PMID: 32814020
In this issue of Immunity, Xu et al. reveal that dermal dendritic cells produce interleukin-31, which acts on neurons to promote wound itch. Their findings link itch associated with deeper...
3.
Wang F, Yang T, Kim B
J Invest Dermatol
. 2020 Apr;
140(5):945-951.
PMID: 32248995
The mast cell-nerve unit classically has represented a fundamental neuroimmune axis in the development of itch because of the traditional prominence of histamine as a pruritogen. However, it is appreciated...
4.
Mack M, Brestoff J, Berrien-Elliott M, Trier A, Yang T, McCullen M, et al.
Sci Transl Med
. 2020 Feb;
12(532).
PMID: 32102931
Atopic dermatitis (AD) is a widespread, chronic skin disease associated with aberrant allergic inflammation. Current treatments involve either broad or targeted immunosuppression strategies. However, enhancing the immune system to control...
5.
Yang T, Kim B
J Allergy Clin Immunol
. 2019 Aug;
144(2):353-360.
PMID: 31395149
Although evolutionarily conserved to expel ectoparasites and aid in the clearance of toxins and noxious environmental stimuli from the host, the type 2 immune response can become pathologic in the...
6.
Yang T, Chen Q, Deng J, Jagannathan G, Tobias J, Schultz D, et al.
Nat Commun
. 2017 Mar;
8:14766.
PMID: 28303901
Critical telomere shortening (for example, secondary to partial telomerase deficiency in the rare disease dyskeratosis congenita) causes tissue pathology, but underlying mechanisms are not fully understood. Mice lacking telomerase (for...
7.
Yang T, McMahon P, De Leon D, Treat J
Pediatr Dermatol
. 2016 Aug;
33(6):e381-e384.
PMID: 27574111
Infantile hemangiomas (IHs) are the most common pediatric vascular tumors. They require therapy when they cause severe complications such as ulceration, amblyopia, or airway constriction. Propranolol is the only treatment...
8.
Woo D, Chen Q, Yang T, Glineburg M, Hoge C, Leu N, et al.
Cell Stem Cell
. 2016 Aug;
19(3):397-405.
PMID: 27545506
Patients with dyskeratosis congenita (DC) suffer from stem cell failure in highly proliferative tissues, including the intestinal epithelium. Few therapeutic options exist for this disorder, and patients are treated primarily...
9.
Gwiazda K, Yang T, Lin Y, Johnson J
Am J Physiol Endocrinol Metab
. 2009 Jan;
296(4):E690-701.
PMID: 19141690
There are strong links between obesity, elevated free fatty acids, and type 2 diabetes. Specifically, the saturated fatty acid palmitate has pleiotropic effects on beta-cell function and survival. In the...
10.
Luciani D, Gwiazda K, Yang T, Kalynyak T, Bychkivska Y, Frey M, et al.
Diabetes
. 2008 Nov;
58(2):422-32.
PMID: 19033399
Objective: Endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of diabetes, but the roles of specific ER Ca(2+) release channels in the ER stress-associated apoptosis pathway remain unknown....