Thomas Haselhorst
Overview
Explore the profile of Thomas Haselhorst including associated specialties, affiliations and a list of published articles.
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Articles
71
Citations
974
Followers
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Recent Articles
1.
Hansman G, Reese T, Pancera M, Rudd P, Masic V, Haselhorst T, et al.
J Virol
. 2024 Nov;
98(12):e0167524.
PMID: 39513720
No abstract available.
2.
Taha , Eskandari S, Slesarenko V, Haselhorst T, Semchenko E, Seib K
Vaccine
. 2024 Oct;
42(26):126416.
PMID: 39368128
Neisseria gonorrhoeae has a significant impact on reproductive health with an estimated 82 million new cases of infection per year worldwide. Due to the ongoing emergence of multidrug-resistant N. gonorrhoeae...
3.
Rudd P, Kher G, Tame J, Irie H, Haselhorst T, von Itzstein M, et al.
J Virol
. 2024 Jul;
98(7):e0086524.
PMID: 38953656
No abstract available.
4.
Hansman G, Kher G, Svirina A, Tame J, Hartley-Tassell L, Irie H, et al.
J Virol
. 2024 Jul;
98(7):e0070724.
PMID: 38953655
Human norovirus was discovered more than five decades ago and is a widespread cause of outbreaks of acute gastroenteritis. There are no approved vaccines or antivirals currently available. However, norovirus...
5.
Day C, Favuzza P, Bielfeld S, Haselhorst T, Seefeldt L, Hauser J, et al.
Cell Rep
. 2024 Apr;
43(4):114012.
PMID: 38573856
Plasmodium falciparum is a human-adapted apicomplexan parasite that causes the most dangerous form of malaria. P. falciparum cysteine-rich protective antigen (PfCyRPA) is an invasion complex protein essential for erythrocyte invasion....
6.
Rahaman M, Thygesen S, Maxwell M, Kim H, Mudai P, Nanson J, et al.
J Enzyme Inhib Med Chem
. 2024 Feb;
39(1):2313055.
PMID: 38416868
Toll-like receptor (TLR) innate immunity signalling protects against pathogens, but excessive or prolonged signalling contributes to a range of inflammatory conditions. Structural information on the TLR cytoplasmic TIR (Toll/interleukin-1 receptor)...
7.
Farr D, Haselhorst T, Tan L, Furness J, Strong E, Grice I, et al.
Eur J Med Chem
. 2023 Dec;
264:115983.
PMID: 38048695
Simple alkyl-sulfonylacetamides have potent antitubercular activity and significantly decrease mycolic acid levels in mycobacteria. Although these compounds were originally designed to inhibit the ketoacyl synthase domain of fatty acid synthase,...
8.
Haselhorst T
Magn Reson Chem
. 2023 Sep;
62(5):337-344.
PMID: 37776196
Virus-glycan interactions play a crucial role in the infection process of many viruses. NMR spectroscopy has emerged as a powerful tool for studying these interactions at the molecular level. In...
9.
Musik J, Poole J, Day C, Haselhorst T, Jen F, Ve T, et al.
Microbiol Spectr
. 2023 Apr;
11(3):e0500522.
PMID: 37098897
Escherichia coli signal peptidase I (LepB) has been shown to inefficiently cleave secreted proteins with aromatic amino acids at the second position after the signal peptidase cleavage site (P2'). The...
10.
Tosh N, Watson J, Lukas D, Tremewan R, Beard J, Galloway G, et al.
NMR Biomed
. 2023 Mar;
:e4934.
PMID: 36940008
There is a requirement for an objective method to determine a safe level of low-level military occupational blast, having recognised it can lead to neurological damage. The purpose of the...