Jeffrey C Dyason
Overview
Explore the profile of Jeffrey C Dyason including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
26
Citations
436
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Hadhazi A, Li L, Bailly B, Maggioni A, Martin G, Dirr L, et al.
ChemMedChem
. 2018 Feb;
13(8):785-789.
PMID: 29453852
Influenza virus infection continues to cause significant, often severe, respiratory illness worldwide. A validated target for the development of anti-influenza agents is the virus surface protein sialidase. In the current...
2.
Hadhazi A, Pascolutti M, Bailly B, Dyason J, Borbas A, Thomson R, et al.
Org Biomol Chem
. 2017 May;
15(25):5249-5253.
PMID: 28540971
A new direction for influenza virus sialidase inhibitor development was identified using a sulfonate congener of 2-deoxy-2-β-H N-acetylneuraminic acid. Sialosyl sulfonates can be synthesised efficiently in four steps from N-acetylneuraminic...
3.
Bohlmann L, Tredwell G, Yu X, Chang C, Haselhorst T, Winger M, et al.
Nat Chem Biol
. 2015 Nov;
11(12):955-7.
PMID: 26565989
We report the structural and functional characterization of a novel heparanase (BpHep) from the invasive pathogenic bacterium Burkholderia pseudomallei (Bp), showing ∼24% sequence identity with human heparanase (hHep). Site-directed mutagenesis...
4.
Guillon P, Dirr L, El-Deeb I, Winger M, Bailly B, Haselhorst T, et al.
Nat Commun
. 2014 Oct;
5:5268.
PMID: 25327774
Human parainfluenza viruses (hPIVs) cause upper and lower respiratory tract disease in children that results in a significant number of hospitalizations and impacts health systems worldwide. To date, neither antiviral...
5.
El-Deeb I, Guillon P, Winger M, Eveno T, Haselhorst T, Dyason J, et al.
J Med Chem
. 2014 Sep;
57(18):7613-23.
PMID: 25198831
Human parainfluenza virus type 1 is the major cause of croup in infants and young children. There is currently neither vaccine nor clinically effective treatment for parainfluenza virus infection. Hemagglutinin-neuraminidase...
6.
Rudrawar S, Dyason J, Maggioni A, Thomson R, von Itzstein M
Bioorg Med Chem
. 2013 Jun;
21(16):4820-30.
PMID: 23800724
Novel 3,4-disubstituted-Neu5Ac2en derivatives have been synthesised to probe the open 150-loop conformation of influenza virus sialidases. Both equatorially and axially (epi) substituted C4 amino and guanidino 3-(p-tolyl)allyl-Neu5Ac2en derivatives were prepared,...
7.
Swaminathan K, Dyason J, Maggioni A, von Itzstein M, Downard K
Anal Bioanal Chem
. 2013 Jun;
405(20):6563-72.
PMID: 23748498
The binding of a natural anthocyanin to influenza neuraminidase has been studied employing mass spectrometry and molecular docking. Derived from a black elderberry extract, cyanidin-3-sambubiocide has been found to be...
8.
Bhatt B, Bohm R, Kerry P, Dyason J, Russell R, Thomson R, et al.
J Med Chem
. 2012 Sep;
55(20):8963-8.
PMID: 23017008
A series of C3 O-functionalized 2-acetamido-2-deoxy-Δ⁴-β-D-glucuronides were synthesized to explore noncharge interactions in subsite 2 of the influenza virus sialidase active site. In complex with A/N8 sialidase, the parent compound...
9.
Rudrawar S, Kerry P, Rameix-Welti M, Maggioni A, Dyason J, Rose F, et al.
Org Biomol Chem
. 2012 Sep;
10(43):8628-39.
PMID: 22976385
Novel 3-C-alkylated-Neu5Ac2en derivatives have been designed to target the expanded active site cavity of influenza virus sialidases with an open 150-loop, currently seen in X-ray crystal structures of influenza A...
10.
Lai J, Garcia J, Dyason J, Bohm R, Madge P, Rose F, et al.
Angew Chem Int Ed Engl
. 2012 Jan;
51(9):2221-4.
PMID: 22281708
No abstract available.