Thomas D Bannister
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Explore the profile of Thomas D Bannister including associated specialties, affiliations and a list of published articles.
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52
Citations
949
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Recent Articles
1.
Otsuka Y, Kim E, Krueger A, Shumate J, Wang C, Bdiri B, et al.
SLAS Discov
. 2024 Aug;
29(6):100180.
PMID: 39173831
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for nearly 7 million deaths worldwide since its outbreak in late 2019. Even with the rapid development and production of vaccines...
2.
Otsuka Y, Zhang L, Mou H, Shumate J, Kitzmiller C, Scampavia L, et al.
SLAS Discov
. 2024 Aug;
29(6):100178.
PMID: 39159824
Emerging highly pathogenic viruses can pose profound impacts on global health, the economy, and society. To meet that challenge, the National Institute of Allergy and Infectious Diseases (NIAID) established nine...
3.
Diez J, Selsted M, Bannister T, Minond D
Pharmaceuticals (Basel)
. 2024 Jan;
17(1).
PMID: 38256920
Rheumatoid arthritis is a systemic autoimmune inflammatory disease that affects millions of people worldwide. There are multiple disease-modifying anti-rheumatic drugs available; however, many patients do not respond to any treatment....
4.
Tavares M, Kruger A, Yan S, Waitman K, Gomes V, de Oliveira D, et al.
Sci Rep
. 2023 Nov;
13(1):21006.
PMID: 38030668
We report a series of 1,3-diphenylureido hydroxamate HDAC inhibitors evaluated against sensitive and drug-resistant P. falciparum strains. Compounds 8a-d show potent antiplasmodial activity, indicating that a phenyl spacer allows improved...
5.
HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents
Waitman K, de Almeida L, Primi M, Carlos J, Ruiz C, Kronenberger T, et al.
Eur J Med Chem
. 2023 Nov;
263:115935.
PMID: 37989057
A series of hybrid inhibitors, combining pharmacophores of known kinase inhibitors bearing anilino-purines (ruxolitinib, ibrutinib) and benzohydroxamate HDAC inhibitors (nexturastat A), were generated in the present study. The compounds have...
6.
Coant N, Bickel J, Rahaim R, Otsuka Y, Choi Y, Xu R, et al.
Bioorg Chem
. 2023 Aug;
139:106747.
PMID: 37531819
Ceramides impact a diverse array of biological functions and have been implicated in disease pathogenesis. The enzyme neutral ceramidase (nCDase) is a zinc-containing hydrolase and mediates the metabolism of ceramide...
7.
Acevedo-Canabal A, Grim T, Schmid C, McFague N, Stahl E, Kennedy N, et al.
Biomolecules
. 2023 Jun;
13(6).
PMID: 37371516
Opioid analgesics such as morphine and fentanyl induce mu-opioid receptor (MOR)-mediated hyperactivity in mice. Herein, we show that morphine, fentanyl, SR-17018, and oliceridine have submaximal intrinsic efficacy in the mouse...
8.
Smith E, Davis-Gardner M, Garcia-Ordonez R, Nguyen T, Hull M, Chen E, et al.
SLAS Discov
. 2023 Jan;
28(3):95-101.
PMID: 36646172
The SARS coronavirus 2 (SARS-CoV-2) pandemic remains a major problem in many parts of the world and infection rates remain at extremely high levels. This high prevalence drives the continued...
9.
Mediouni S, Mou H, Otsuka Y, Jablonski J, Adcock R, Batra L, et al.
SLAS Discov
. 2022 Jan;
27(1):8-19.
PMID: 35058179
The severe acute respiratory syndrome coronavirus 2 responsible for COVID-19 remains a persistent threat to mankind, especially for the immunocompromised and elderly for which the vaccine may have limited effectiveness....
10.
Stahl E, Schmid C, Acevedo-Canabal A, Read C, Grim T, Kennedy N, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(48).
PMID: 34819362
The ability of a ligand to preferentially promote engagement of one signaling pathway over another downstream of GPCR activation has been referred to as signaling bias, functional selectivity, and biased...