Thomas C Kaufman
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Explore the profile of Thomas C Kaufman including associated specialties, affiliations and a list of published articles.
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58
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6722
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Recent Articles
11.
Cook R, Christensen S, Deal J, Coburn R, Deal M, Gresens J, et al.
Genome Biol
. 2012 Mar;
13(3):R21.
PMID: 22445104
Background: Chromosomal deletions are used extensively in Drosophila melanogaster genetics research. Deletion mapping is the primary method used for fine-scale gene localization. Effective and efficient deletion mapping requires both extensive...
12.
Graveley B, Brooks A, Carlson J, Duff M, Landolin J, Yang L, et al.
Nature
. 2010 Dec;
471(7339):473-9.
PMID: 21179090
Drosophila melanogaster is one of the most well studied genetic model organisms; nonetheless, its genome still contains unannotated coding and non-coding genes, transcripts, exons and RNA editing sites. Full discovery...
13.
Roy S, Ernst J, Kharchenko P, Kheradpour P, Negre N, Eaton M, et al.
Science
. 2010 Dec;
330(6012):1787-97.
PMID: 21177974
To gain insight into how genomic information is translated into cellular and developmental programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) project is comprehensively mapping transcripts, histone modifications,...
14.
Cherbas L, Willingham A, Zhang D, Yang L, Zou Y, Eads B, et al.
Genome Res
. 2010 Dec;
21(2):301-14.
PMID: 21177962
Drosophila melanogaster cell lines are important resources for cell biologists. Here, we catalog the expression of exons, genes, and unannotated transcriptional signals for 25 lines. Unannotated transcription is substantial (typically...
15.
Hoskins R, Landolin J, Brown J, Sandler J, Takahashi H, Lassmann T, et al.
Genome Res
. 2010 Dec;
21(2):182-92.
PMID: 21177961
Core promoters are critical regions for gene regulation in higher eukaryotes. However, the boundaries of promoter regions, the relative rates of initiation at the transcription start sites (TSSs) distributed within...
16.
Venken K, Popodi E, Holtzman S, Schulze K, Park S, Carlson J, et al.
Genetics
. 2010 Sep;
186(4):1111-25.
PMID: 20876565
We describe a molecularly defined duplication kit for the X chromosome of Drosophila melanogaster. A set of 408 overlapping P[acman] BAC clones was used to create small duplications (average length...
17.
Cook R, Deal M, Deal J, Garton R, Brown C, Ward M, et al.
Genetics
. 2010 Sep;
186(4):1095-109.
PMID: 20876560
Interchromosomal duplications are especially important for the study of X-linked genes. Males inheriting a mutation in a vital X-linked gene cannot survive unless there is a wild-type copy of the...
18.
Robinson R, Kellie J, Kaufman T, Clemmer D
Mech Ageing Dev
. 2010 Aug;
131(9):584-90.
PMID: 20732347
Drosophila melanogaster is used as a model system to investigate protein changes associated with the aging process under conditions that alter organism lifespan. Changes in the proteome are assessed at...
19.
Cook K, Parks A, Jacobus L, Kaufman T, Matthews K
Fly (Austin)
. 2010 Feb;
4(1):88-91.
PMID: 20160480
The Bloomington Drosophila Stock Center (BDSC) is a primary source of Drosophila stocks for researchers all over the world. It houses over 27,000 unique fly lines and distributed over 160,000...
20.
Liu P, Kaufman T
Cold Spring Harb Protoc
. 2010 Feb;
2009(8):pdb.prot5262.
PMID: 20147238
No abstract available.