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Kevin R Cook

Explore the profile of Kevin R Cook including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 1192
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Recent Articles
1.
Weasner B, Weasner B, Cook K, Stinchfield M, Kondo S, Saito K, et al.
G3 (Bethesda) . 2025 Jan; PMID: 39804955
As part of an ongoing effort to generate comprehensive resources for the experimental analysis of fourth chromosome genes in Drosophila melanogaster, the Fourth Chromosome Resource Project has used CRISPR mutagenesis...
2.
Kolesnikova T, Klenov M, Nokhova A, Lavrov S, Pokholkova G, Schubert V, et al.
Cells . 2022 Dec; 11(23). PMID: 36497131
The pericentromeric heterochromatin is largely composed of repetitive sequences, making it difficult to analyze with standard molecular biological methods. At the same time, it carries many functional elements with poorly...
3.
Holsopple J, Cook K, Popodi E
MicroPubl Biol . 2022 Sep; 2022. PMID: 36065255
In , hormone-secreting enteroendocrine cells are important for communication from the midgut to other tissues. Many lexA, GAL4, and split-GAL4 drivers that direct gene expression in enteroendocrine cells also confer...
4.
Holsopple J, Cook K, Popodi E
G3 (Bethesda) . 2022 Apr; 12(6). PMID: 35485968
The Drosophila melanogaster midgut is commonly studied as a model epithelial tissue for many reasons, one of which is the presence of a diverse population of secretory cells called enteroendocrine...
5.
Ariyapala I, Holsopple J, Popodi E, Hartwick D, Kahsai L, Cook K, et al.
Genetics . 2020 Sep; 216(4):891-903. PMID: 32988987
The adult midgut is a model epithelial tissue composed of a few major cell types with distinct regional identities. One of the limitations to its analysis is the lack of...
6.
Miller D, Kahsai L, Buddika K, Dixon M, Kim B, Calvi B, et al.
G3 (Bethesda) . 2020 Sep; 10(11):4271-4285. PMID: 32972999
Balancers are rearranged chromosomes used in to maintain deleterious mutations in stable populations, preserve sets of linked genetic elements and construct complex experimental stocks. Here, we assess the phenotypes associated...
7.
Miller D, Cook K, Hawley R
PLoS Genet . 2019 Nov; 15(11):e1008421. PMID: 31697682
Balancer chromosomes are multiply inverted and rearranged chromosomes that are widely used in Drosophila genetics. First described nearly 100 years ago, balancers are used extensively in stock maintenance and complex...
8.
Benner L, Castro E, Whitworth C, Venken K, Yang H, Fang J, et al.
Genetics . 2019 Sep; 213(3):877-895. PMID: 31558581
Heterochromatin-mediated repression is essential for controlling the expression of transposons and for coordinated cell type-specific gene regulation. The () locus was identified in a screen for female-sterile mutations in ,...
9.
Miller D, Cook K, Hemenway E, Fang V, Miller A, Hales K, et al.
G3 (Bethesda) . 2018 Feb; 8(4):1161-1171. PMID: 29420191
Balancer chromosomes are multiply inverted and rearranged chromosomes used in for many tasks, such as maintaining mutant alleles in stock and complex stock construction. Balancers were created before molecular characterization...
10.
Kahsai L, Cook K
G3 (Bethesda) . 2017 Oct; 8(1):9-16. PMID: 29066472
Hundreds of stocks are currently maintained at the Bloomington Stock Center with mutations that have not been associated with sequence-defined genes. They have been preserved because they have interesting loss-of-function...